Social Networks and HIV-infected Former Prison Inmates
社交网络和感染艾滋病毒的前监狱囚犯
基本信息
- 批准号:7494912
- 负责人:
- 金额:$ 22.14万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2008
- 资助国家:美国
- 起止时间:2008-09-19 至 2010-06-30
- 项目状态:已结题
- 来源:
- 关键词:AcuteAddressAttitudeBehaviorBiological MarkersCaringCase ManagementCharacteristicsClothingCommunitiesCrack CocaineDataDrug usageEpidemicFaceFamilyFoodFreedomFundingGenerationsGeneticGenetic VariationGenotypeGoalsHIVHealthHealth Services AccessibilityIllicit DrugsImprisonmentImprove AccessIndividualInterventionJoint DislocationLeftMapsMedicalMinorityMolecular EpidemiologyNetwork-basedNorth CarolinaNoseNumbersOrganismOutcomePatient Self-ReportPersonal SatisfactionPharmaceutical PreparationsPilot ProjectsPlayPopulationPositioning AttributePrevalencePrisonerPrisonsPublic HealthRandomized Controlled Clinical TrialsRateRecruitment ActivityResistanceRespondentRiskRisk BehaviorsRisk-TakingRoleSamplingSeriesSexual PartnersSexually Transmitted DiseasesShelter facilitySocial NetworkSourceStaphylococcus aureusStructureSubstance abuse problemSystemTimeValidity of Self Reportabstractingbacterial geneticsbasecondomsimprovedintravenous drug usemembermethicillin resistant Staphylococcus aureusnovelpathogenprogramsself reported behaviorsocialstemtooltransmission processtreatment program
项目摘要
DESCRIPTION (provided by applicant): Project Summary/Abstract Release from prison is a time of serious dislocation and significant challenges to the well being of the HIV-infected former inmate as well as to their social networks and the communities to which they return. Not only must the pressing exigent questions of food, clothing and shelter be addressed, s/he must also re- integrate into family and social networks. These challenges are particularly acute for the HIV-infected former inmate who, in addition to meeting the needs described above, must also establish a relationship with a regular source of medical care and find a way to pay for expensive medications. Despite the public health implications of the drug and sexual risk taking of these individuals, there have been few comprehensive assessments of the risk behaviors of HIV-infected releasees. Our preliminary data indicate that HIV-infected former inmates frequently have multiple sexual partners and low rates of condom usage. A large number of studies have established a central role for social networks in defining HIV risk behaviors. Social network-based studies of HIV-infected individuals have relied largely on respondent- driven sampling/recruiting (RDS). RDS strategies have been helpful in mapping connections; however, strategies that rely on self-report to characterize behavior that is stigmatized and illegal face significant limitations. These approaches are particularly problematic in characterizing networks in which partnerships may be anonymous. Given the critical role that interactions between network members play in influencing the spread of the HIV epidemic and the concerns regarding the validity of self-reported behavior, novel and robust approaches are required to provide a more complete understanding of these social structures. In this R21 application, we propose to conduct a preliminary assessment of the utility of a biomarker for social network involvement by HIV-infected former inmates; specifically, we will characterize the molecular epidemiology of nasal colonization with Staphylococcus aureus (SA). Our goal is to determine whether nasal carriage with SA can be used both to verify an epidemiologic connection as well as to identify connections among people that were previously unknown. In this series of pilot studies, we will: 1) Characterize SA nasal colonization among 250 HIV-infected inmates incarcerated in the North Carolina Department of Corrections (NCDOC). 2) Characterize the relationship between SA genotypes and social network characteristics among HIV- infected former inmates who are colonized with SA. Project Narrative Despite the public health implications of the drug and sexual risk taking of prison releasees, there have been few comprehensive assessments of the risk behaviors of HIV-infected releasees. Strategies that rely on self-report to characterize behavior that is stigmatized and illegal face significant limitations; therefore, we propose to conduct a preliminary assessment of the utility of a biomarker for social network involvement by HIV-infected former inmates.
描述(由申请人提供):项目摘要/摘要从监狱释放是一个严重的错位和重大挑战的时间,以健康的艾滋病毒感染的前囚犯,以及他们的社交网络和社区,他们返回。不仅必须解决紧迫的食物、衣服和住所问题,她/他还必须重新融入家庭和社交网络。这些挑战对于感染艾滋病毒的前囚犯来说尤其严重,他们除了满足上述需求外,还必须与正规医疗机构建立关系,并设法支付昂贵的药物费用。尽管这些人的药物和性冒险对公共卫生有影响,但对艾滋病毒感染者的风险行为很少有全面的评估。我们的初步数据表明,感染艾滋病毒的前囚犯往往有多个性伴侣,安全套使用率低。大量的研究已经确立了社交网络在定义艾滋病毒风险行为方面的核心作用。基于社交网络的HIV感染者研究主要依赖于应答者驱动的抽样/招募(RDS)。RDS策略有助于映射连接;然而,依赖于自我报告来描述被污名化和非法行为的策略面临着很大的局限性。这些方法在确定伙伴关系可能是匿名的网络的特征方面特别成问题。考虑到网络成员之间的互动在影响艾滋病毒流行病的传播方面发挥的关键作用,以及对自我报告行为有效性的关注,需要新的和强大的方法来更全面地了解这些社会结构。在这个R21应用程序中,我们建议进行初步评估的效用的生物标志物的社会网络参与艾滋病毒感染的前囚犯,具体来说,我们将表征鼻腔定植金黄色葡萄球菌(SA)的分子流行病学。我们的目标是确定SA的鼻携带是否可以用于验证流行病学联系以及识别以前未知的人之间的联系。在这一系列的试点研究中,我们将:1)表征SA鼻腔定植在250名艾滋病毒感染的囚犯监禁在北卡罗来纳州惩教署(NCDOC)。2)描述SA基因型和社会网络特征之间的关系,在HIV感染的前囚犯谁是SA殖民。项目叙述尽管公共卫生的影响,毒品和性风险的监狱释放,有一些全面的评估艾滋病毒感染的释放的风险行为。策略,依靠自我报告来表征的行为,是污名化和非法面临着重大的局限性,因此,我们建议进行初步评估的效用的生物标志物的社会网络参与艾滋病毒感染的前囚犯。
项目成果
期刊论文数量(0)
专著数量(0)
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会议论文数量(0)
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CAROL E GOLIN其他文献
CAROL E GOLIN的其他文献
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{{ truncateString('CAROL E GOLIN', 18)}}的其他基金
Community Engagement to Enhance EBI Implementation in a Public Housing Community
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- 批准号:
8921665 - 财政年份:2015
- 资助金额:
$ 22.14万 - 项目类别:
Community Engagement to Enhance EBI Implementation in a Public Housing Community
社区参与以加强公共住房社区的 EBI 实施
- 批准号:
9281080 - 财政年份:2015
- 资助金额:
$ 22.14万 - 项目类别:
Mentoring Junior Investigators: Comprehensive HIV Prevention
指导初级研究者:全面的艾滋病毒预防
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Mentoring Junior Investigators: Comprehensive HIV Prevention
指导初级研究者:全面的艾滋病毒预防
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8735975 - 财政年份:2013
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$ 22.14万 - 项目类别:
Mentoring Junior Investigators: Comprehensive HIV Prevention
指导初级研究者:全面的艾滋病毒预防
- 批准号:
8542136 - 财政年份:2013
- 资助金额:
$ 22.14万 - 项目类别:
Social Networks and HIV-infected Former Prison Inmates
社交网络和感染艾滋病毒的前监狱囚犯
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