Training Program in Trauma and Organ Injury

创伤和器官损伤培训计划

• 批准号: 7455062
• 负责人: ROBERT N. COONEY
• 金额: $ 11.35万
• 依托单位: PENNSYLVANIA STATE UNIV HERSHEY MED CTR
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-07-01 至 2012-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7455062
• 关键词: Injury; Organ; Training Programs; Trauma

DESCRIPTION (provided by applicant): Traumatic injury continues to be a major public health problem that impacts enormously on individuals and society. An essential component of the trauma health care system is basic and clinical research. However, future advancements in trauma research are likely to be hindered because of the continued decline in the number of well-trained physician-scientists. This is the first competing renewal of a postdoctoral training program in Trauma Biology and Organ Injury. The Training Program is designed primarily for surgical residents (PGY-III and IV) to provide them with an intensive two (or three)-year period of research focused on the mechanisms responsible for the cellular dysfunction and multiorgan failure associated with injury. It will complement the ongoing trauma research programs already present in the Departments of Surgery, and Cellular and Molecular Physiology. The goal of the training program is to provide highly qualified, motivated individuals with an in-depth knowledge base and intensive laboratory experience that will facilitate a successful, productive independent career in academic trauma research. The specific aims of the training program are to: (1) provide comprehensive scientific training focused in one of two major disciplines--Endocrinology and Metabolism, and Organ Injury and Tissue Repair; and (2) provide a strong training foundation in all aspects of the investigative process. The administrative structure of the program is coordinated by the Program Director (Wiley Souba, MD) and Associate Director (Charles Lang, PhD). Each trainee selects co-mentors (e.g., one clinician-scientist and one basic scientist) from an interdisciplinary cadre of established investigators within the Departments of Surgery, Cellular and Molecular Physiology, Orthopedics, Internal Medicine, and Pharmacology which are responsible for directing and evaluating the trainee's progress. Trainees will receive direct supervision regarding all aspects of hypothesis-driven experimental design, technical expertise, and scientific writing as well as participate in the required course on ethical conduct in research. Program graduates will be clinician-scientists who possess sufficient scientific maturity to embark on a career in independent research and make significant contributions to the advancement of knowledge concerning the pathophysiology of trauma.

描述（由申请人提供）：创伤性伤害仍然是一个对个人和社会产生巨大影响的主要公共卫生问题。创伤医疗保健系统的一个重要组成部分是基础和临床研究。然而，由于训练有素的医师科学家数量持续下降，创伤研究的未来进展可能会受到阻碍。这是创伤生物学和器官损伤领域博士后培训项目的首次竞争更新。该培训计划主要为外科住院医师（PGY-III 和 IV）设计，为他们提供为期两年（或三年）的强化研究，重点关注与损伤相关的细胞功能障碍和多器官衰竭的机制。它将补充外科、细胞和分子生理学系现有的正在进行的创伤研究项目。培训计划的目标是为高素质、积极进取的个人提供深入的知识基础和丰富的实验室经验，这将有助于他们在学术创伤研究方面取得成功、富有成效的独立职业生涯。培训项目的具体目标是：（1）围绕内分泌与代谢、器官损伤与组织修复两大学科之一提供全面的科学培训； (2) 为调查过程的各个方面提供坚实的培训基础。该项目的行政结构由项目总监（医学博士 Wiley Souba）和副总监（查尔斯·朗博士）负责协调。每位学员从外科、细胞和分子生理学、骨科、内科和药理学等部门的跨学科骨干研究人员中选择共同导师（例如一名临床科学家和一名基础科学家），负责指导和评估学员的进步。学员将接受关于假设驱动的实验设计、技术专业知识和科学写作各个方面的直接监督，并参加研究道德行为的必修课程。项目毕业生将成为临床医生科学家，他们拥有足够的科学成熟度，可以从事独立研究职业，并为创伤病理生理学知识的进步做出重大贡献。