Clinical Scholars Biomedical Research Training Program

描述（由申请人提供）：斯隆-凯特琳研究所纪念斯隆-凯特琳癌症中心（MSKCC）的临床学者生物医学研究培训计划为一组杰出的医学博士或医学博士/博士提供癌症研究的指导实验室培训经验。这项培训将为癌症生物学和临床研究界面的职业生涯准备高素质的医生科学家。申请了7个职位。研究员由从斯隆-凯特琳研究所专业人员中抽调的主要调查员培训。一个结构化和有凝聚力的为期两年的培训计划已被设计为提供指导实验室研究，现代生物学和生物信息学和职业发展技能的教学课程工作出色的导师。学员可以使用纪念斯隆-凯特琳癌症中心的所有资源。主要研究领域包括：1）参与细胞增殖控制的信号和途径; 2）参与发育生物学和细胞分化的调控途径; 3）细胞-细胞相互作用，粘附和蛋白质靶向; 4）肿瘤免疫学，免疫治疗和移植生物学; 5）人类癌症生物学，癌症小鼠模型，遗传学和分子病理学;和6）药物开发和治疗。接受该计划培训的医生科学家将更容易将生物医学，癌症相关研究的最新革命性发现转化为患者护理。

DESCRIPTION (provided by applicant): The Clinical Scholars Biomedical Research Training Program at Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center (MSKCC) provides a mentored laboratory training experience in cancer research for a group of outstanding MDs or MD/PhDs. This training will prepare highly qualified physician-scientists for a career at the interface of cancer biology and clinical research. Seven positions are requested. The fellows are trained by principal investigators, drawn from the professional staff of Sloan-Kettering Institute. A structured and cohesive two-year training program has been designed to provide outstanding mentorship in guided laboratory research, didactic course work in modern biology and bioinformatics and career development skills. Trainees have access to all resources of the Memorial Sloan-Kettering Cancer Center. The areas of principal emphasis for research include: 1) Signals and pathways involved in control of cell proliferation; 2) Regulatory pathways involved in developmental biology and cell differentiation; 3) Cell-cell interactions, adhesion and protein targeting; 4) Tumor immunology, immunotherapy and transplantation biology; 5) Human cancer biology, mouse models of cancer, genetics and molecular pathology; and 6) Drug development and therapeutics. Physicians-scientists receiving training from this program will be poised to more readily translate the recent revolutionary discoveries of biomedical, cancer-related research into patient care.