Neurologic Clinical Epidemiology Training Program

描述（由申请人提供）：临床流行病学和生物统计学中心（CCEB）和宾夕法尼亚大学（Penn）医学院（SOM）神经病学系与费城儿童医院神经病学部儿科合作，提议开发一个创新的博士后神经病学临床流行病学培训计划。宾大和SOM促进了一个学术环境，在这个环境中，基础和临床研究受到鼓励，并被视为对学员有吸引力的职业道路。该机构还吸引了来自全国其他机构的学员，从而促进了思想和指导方式的交流。该计划专门设计用于培训已经接受过神经病学培训的临床医生成为严谨，独立的学术研究人员，能够使用流行病学中可用的一系列方法来解决有关病因，预后，预防和早期检测，治疗，临床经济学，技术评估，医疗决策和神经疾病患者护理质量的临床研究问题。具体而言，学员将临床流行病学的方法应用于神经病学的广泛子专业，包括神经眼科学，多发性硬化症，神经肿瘤学，癫痫，认知神经学，中风和运动障碍。两年至三年的培训计划包括临床流行病学，研究方法学，生物统计学和神经病学临床流行病学的必修课程;专注于神经病学研究问题的期刊俱乐部和临床研究会议;广泛的独立阅读;出席并参与CCEB，神经病学系和神经病学系的研究研讨会（儿科）;并完成一个独立的研究项目。具体而言，该计划旨在：1）提供适合临床研究的研究技术的深入知识; 2）提供临床流行病学和神经病学研究导师的研究经验; 3）汇集CCEB，神经病学系和神经病学（儿科）系的教师和研究员。受训者在临床流行病学（MSCE）学位课程，这是由CCEB管理的科学硕士录取。该计划的优势是：1）CCEB成功的研究培训计划的悠久历史; 2）可供学员使用的全面课程和研究计划; 3）CCEB，神经病学系和神经病学系之间存在的合作联系（儿科）; 4）和一个广泛的一套经验丰富的项目总监和教师导师与成功的培训记录。此外，CCEB，神经病学系和神经病学（儿科）系的教师的广泛丰富的专业知识的可用性;许多现有的大型数据库可用于研究项目和培训;广泛的专业分析能力可用于临床研究（即，临床试验，病例对照，队列研究）;和学院的合作研究和培训的承诺，为这个培训计划提供了一个理想的环境。

DESCRIPTION (provided by applicant): The Center for Clinical Epidemiology and Biostatistics (CCEB) and the Department of Neurology of the University of Pennsylvania (Penn) School of Medicine (SOM), in collaboration with the Department of Pediatrics, Division of Neurology, of Children's Hospital of Philadelphia propose to develop an innovative postdoctoral neurologic clinical epidemiology training program. Penn and the SOM promote an academic environment in which basic and clinical research are encouraged and viewed as attractive career paths for trainees. The institution also attracts trainees from other institutions nationwide, thus promoting exchange of ideas and mentoring styles. This program is specifically designed to train clinicians already trained in neurology to be rigorous, independent academic investigators able to use the range of approaches available in epidemiology to address clinical research issues regarding the etiology, prognosis, prevention and early detection, treatment, clinical economics, technology assessment, medical decision making, and quality of patient care of neurologic diseases. Specifically, trainees will apply the methods of clinical epidemiology to a broad spectrum of sub-specialties within Neurology, including neuro-ophthalmology, multiple sclerosis, neuron-oncology, epilepsy, cognitive neurology, stroke, and movement disorders. The two- to three-year training program consists of required courses in clinical epidemiology, research methodology, biostatistics, and neurologic clinical epidemiology; journal clubs and clinical research conferences focusing on research issues in neurology; extensive independent readings; attendance at and participation in research seminars at the CCEB, Department of Neurology, and Division of Neurology (Pediatrics); and the completion of an independent research project. Specifically, the program is designed to: 1) provide in-depth knowledge of the research techniques appropriate to clinical research; 2) provide research experience with mentors in clinical epidemiology and neurology research; and 3) bring together faculty and fellows in the CCEB, the Department of Neurology, and the Division of Neurology (Pediatrics). Trainees matriculate in the Master of Science in Clinical Epidemiology (MSCE) degree program, which is managed by the CCEB. Strengths of the proposed program are: 1) the long history of successful research training programs in the CCEB; 2) the comprehensive course offerings and research programs that are available to trainees; 3) the collaborative links that exist among the CCEB, the Department of Neurology, and the Division of Neurology (Pediatrics); 4) and an extensive set of experienced program directors and faculty preceptors with successful training records. In addition, the availability of the broad range of rich expertise of the faculties in the CCEB, Department of Neurology, and Division of Neurology (Pediatrics); numerous existing large databases available that can be used for research projects and training; a broad array of specialized analytic capabilities available for clinical studies (i.e., clinical trials, case-control, cohort research); and the faculties' commitment to collaborative research and training, provide an ideal environment for this training program.