Betahistine: Novel Therapeutic in Attention Deficit Hyperactivity Disorder

倍他司汀：注意力缺陷多动障碍的新疗法

• 批准号: 7478770
• 负责人: JEFFREY M LYNESS
• 金额: $ 12.47万
• 依托单位: UNIVERSITY OF ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-08-01 至 2010-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7478770
• 关键词: Geriatric Psychiatry; Research; post-doctoral training

DESCRIPTION (provided by applicant): This application presents an application for three 3-year fellowship slots to support postdoctoral training in geriatric psychiatry, psychology, and related areas of mental health research, via a new Institutional National Research Service Award (T32). We are creating this geriatrics-specific training program after the intentional broadening of our Department's longstanding NIMH-funded T32 in the 1990s, when we felt that there were too few mentors in the geriatric mentoring group. In recent years, however, our geriatrics research programs and their collaborative resources have continued to grow substantially, thus providing a unique foundation for the development of a translational research focus. Our explicit goal is to train the next generations of physicians and other doctoral trained scientists as future investigators conducting translational (i.e., "bench to bedside" and "clinical research setting to real world practice") interventions and prevention research, primarily related to depression and dementia in later life. Hallmarks of our approach include access to a wide range of subject populations (consistent with the "real world" component of translational research), and a Departmental and University-wide culture placing high values on mentored career development and on multidisciplinary clinical, educational, and research collaborations. Core areas of skill development include: geriatric psychopathology, research design and methods (particularly as they relate to prevention and intervention research), biostatistics, grant writing and writing for publication, and the ethics of research. There are seven (7) mid-career and senior-level faculty members serving as primary Mentors for the proposed fellowship slots, and additional Preceptors and Resource Faculty. Throughout the past 15 years, our Department has recruited highly qualified candidates to our postdoctoral training programs, and our trainees have gone on to successful academic careers as demonstrated through their publications, their successfully funded grant applications, and their promotions. The proposed training is based on the establishment of a committed mentor-trainee relationship, the formulation of individually tailored programs that involve fellows in current research and support the development of their own protocols, and formal didactics-based learning including both required and "selective" courses, seminars, and research meetings. Such training addresses critical "pipeline" shortages in geriatric mental health research.

描述（由申请人提供）：本申请提出了三个为期 3 年的奖学金名额的申请，以通过新的机构国家研究服务奖 (T32) 支持老年精神病学、心理学和心理健康研究相关领域的博士后培训。我们在 20 世纪 90 年代有意扩大我们部门长期由 NIMH 资助的 T32 后，创建了这个针对老年病学的培训计划，当时我们认为老年病学指导小组中的导师太少。然而，近年来，我们的老年病学研究项目及其合作资源持续大幅增长，从而为转化研究重点的发展提供了独特的基础。我们的明确目标是培训下一代医生和其他受过博士学位的科学家作为未来的研究人员进行转化（即“从实验室到床边”和“临床研究设置到现实世界实践”）干预和预防研究，主要与晚年的抑郁症和痴呆症有关。我们方法的特点包括接触广泛的受试者群体（与转化研究的“现实世界”组成部分一致），以及高度重视指导职业发展和多学科临床、教育和研究合作的院系和大学文化。技能发展的核心领域包括：老年精神病理学、研究设计和方法（特别是与预防和干预研究相关的）、生物统计学、资助写作和出版写作以及研究伦理。有七 (7) 名职业生涯中期和高级教师担任拟议奖学金名额的主要导师，以及其他导师和资源教师。在过去的 15 年里，我们系招募了高素质的候选人参加我们的博士后培训项目，我们的学员已经取得了成功的学术生涯，这通过他们的出版物、成功资助的资助申请和晋升来证明。拟议的培训基于建立忠诚的导师与学员关系，制定个性化的计划，让研究员参与当前的研究并支持制定自己的协议，以及正式的基于教学的学习，包括必修和“选择性”课程、研讨会和研究会议。此类培训解决了老年心理健康研究中严重的“渠道”短缺问题。