Improving the Care and Outcomes of Patients with Unhealthy Alcohol Use

描述（由申请人提供）：Kevin L. Kraemer，MD，MSc，匹兹堡大学医学副教授正在申请这项以患者为导向的研究（K24）的职业中期研究者奖。他的中间职业目标是：1）成长为改善酒精筛查和干预在各种临床环境中的领导者，并确定这些策略的成本效益;和2）作为医学实习生（医学生，居民和研究员）和初级教师的导师追求以患者为导向的酒精研究活动和职业。他的长期职业目标是：1）将他的研究技能应用于协作护理模式，以改善不健康酒精使用患者的护理质量和健康结果，2）应用 他在成本效益方法方面的专业知识，以分析协作护理模式和新的 新兴的酒精筛查方法和治疗，3）在匹兹堡大学促进以病人为导向的酒精研究和教育的机构领导者。候选人的以病人为导向的研究将分两个阶段进行。在第一阶段（1-3年），他将指导一项以患者为导向的研究，以衡量一系列酒精问题的患者和社会效用以及生活质量。在第二阶段（3-5年），他将扩大他的研究计划，开发和测试协作护理干预措施，以提高不健康酒精使用的初级保健患者的护理质量和健康结果，并将成本效益方法应用于协作护理模式的分析。在这两个阶段中，由候选人指导的医学实习生和初级教师将融入候选人的研究活动。在获奖过程中，候选人将指导六名医学生和居民，四名临床研究员和五名初级教师进行以患者为导向的酒精研究。研究培训和教育经验，量身定制的学员的水平，将包括一个指导病人为导向的研究项目，参加每周杂志俱乐部，每周的研究研讨会，和全年的研究生水平的课程。拟议的研究和指导计划将在匹兹堡大学进行，该大学对候选人的专业发展有着坚定的机构承诺，并有一个使命，即支持整个健康科学学院的教职员工开展以患者为导向的研究活动。这些学校提供大量的临床研究培训和教育计划，包括由候选人指导的由校外资助的普通内科奖学金计划，以及匹兹堡大学临床和转化科学研究所（CTSI）。

DESCRIPTION (provided by applicant): Kevin L. Kraemer, MD, MSc, Associate Professor of Medicine at the University of Pittsburgh is applying for this mid-career investigator award in patient-oriented research (K24). His intermediate career objectives are: 1) to grow as a leader in improving alcohol screening and intervention in various clinical settings and determining the cost-efficiency of these strategies; and 2) to serve as a mentor for medical trainees (medical students, residents, and fellows) and junior faculty members pursuing patient-oriented alcohol research activities and careers. His long-term career objectives are: 1) to apply his research skills to collaborative care models for improving quality of care and health outcomes for patients with unhealthy alcohol use, 2) to apply his expertise in cost-effectiveness methodology to analysis of collaborative care models and to new emerging alcohol screening methods and treatments, and 3) to be an institutional leader in the promotion of patient-oriented alcohol research and education at the University of Pittsburgh. The candidate's patient-oriented research will be conducted in two phases. During Phase I (Years 1-3), he will direct a patient-oriented study to measure patient and societal utilities and quality of life for a range of alcohol problems. In Phase II (Years 3-5), he will expand his research program to develop and test collaborative care interventions for improving quality of care and health outcomes for primary care patients with unhealthy alcohol use and to apply cost-effectiveness methodology to analysis of collaborative care models. In both phases, medical trainees and junior faculty mentored by the candidate will be integrated into the candidate's research activities. Over the course of the award, the candidate will mentor six medical students and residents, four clinical research fellows, and five junior faculty members in patient-oriented alcohol research. Research training and education experiences, tailored to the level of the mentee, will include a mentored patient-oriented research project, participation in a weekly journal club, weekly research seminars, and year-round graduate-level coursework. The proposed research and mentoring programs will be conducted at the University of Pittsburgh, which has a strong institutional commitment to the professional development of the candidate and a mission to support patient-oriented research activities by faculty members throughout its schools of the health sciences. These schools provide substantial clinical research training and education programs, including a extramurally funded General Internal Medicine Fellowship Program directed by the candidate, and the University of Pittsburgh Clinical and Translational Science Institute (CTSI).