CWRU Clinical Vision Research Initiative

描述(由申请者提供)：R21临床视觉研究发展奖旨在加强凯斯西储大学视觉科学研究中心(VSRC)的临床研究活动和研究人员的能力。CWRU VSRC总部设在眼科，包括30多名视觉科学研究人员，CWRU的12个基础和临床科，以及3家附属医院。VSRC已经建立了一个优秀的基础科学研究计划，目前有17个R01和R03奖项，一个P30核心资助和T32培训资助。VSRC的下一个目标是扩大和加强资源，以建立一个强大的临床视力研究计划。这项R21奖将允许扩大VSRC临床研究单位和创建VSRC生物统计单位，这两个资源对CWRU临床视力研究的继续发展至关重要。在建议项目的医学博士Jonathan Lass和目前的P30 Core Grant、VSRC主任兼CWRU眼科主任Jonathan Lass的指导下，我们的具体目标如下：1)扩大我们现有的临床研究单位的资源、知识和工作人员；2)建立一个生物统计学单位，它将自给自足地服务于我们临床研究人员的所有研究设计、数据分析和数据报告需求；3)最终建立数据协调中心的能力和活动。通过这个R21奖项，再加上强大的基础科学项目和不断扩大的临床科学项目，我们寻求将CWRU VSRC定位为美国领先的视觉科学研究中心之一。

DESCRIPTION (provided by applicant): This R21 Clinical Vision Research Development Award is designed to enhance the clinical research activities and capabilities of investigators in the Visual Sciences Research Center (VSRC) at Case Western Reserve University (CWRU). The CWRU VSRC, based in the Department of Ophthalmology, encompasses over 30 vision science researchers, 12 basic and clinical departments at CWRU, and 3 affiliated hospitals. The VSRC has an already established and excellent basic science research program as evidenced by 17 current R01 and R03 awards, a P30 Core Grant and T32 Training Grant. The next goal of the VSRC is to expand and strengthen resources to establish a strong clinical vision research program. This R21 award will allow for the expansion of the VSRC Clinical Research Unit and the creation of a VSRC Biostatistics Unit, two resources critical to the continued development of clinical vision research at CWRU. Under the direction of Jonathan Lass, M.D., PI of this proposed project and the current P30 Core Grant, Director of the VSRC, and Chairman of the CWRU Department of Ophthalmology, our specific aims are as follows: 1) expand the resources, knowledge, and staff of our existing Clinical Research Unit, 2) establish a Biostatistics Unit which will be self sufficient in serving all the study design, data analysis, and data reporting needs of our clinical investigators, and 3) ultimately establish data coordinating center capabilities and activities. Together with a strong basic science program and an expanding clinical science program made possible through this R21 award, we seek to place the CWRU VSRC as one of the leading visual sciences research centers in this country.