CWRU Clinical Vision Research Initiative

CWRU 临床视觉研究计划

• 批准号: 7386570
• 负责人: JONATHAN H LASS
• 金额: $ 14.56万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-04-01 至 2010-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7386570
• 关键词: Award; Basic Science; Biometry; Cancer Center Support Grant; Chairperson; Clinical; Clinical Investigator; Clinical Research; Clinical Sciences; Country; Data; Data Analyses; Data Coordinating Center; Development; Doctor of Medicine; Environment; Exploratory/Developmental Grant for Diagnostic Cancer Imaging; Goals; Grant; Hospitals; Information Resources; Medical center; Ophthalmology; Participant; Reporting; Research; Research Activity; Research Design; Research Personnel; Resources; Training; Universities; University Hospitals; Vision research; base; design; interest; programs; ranpirnase; research and development; vision science

DESCRIPTION (provided by applicant): This R21 Clinical Vision Research Development Award is designed to enhance the clinical research activities and capabilities of investigators in the Visual Sciences Research Center (VSRC) at Case Western Reserve University (CWRU). The CWRU VSRC, based in the Department of Ophthalmology, encompasses over 30 vision science researchers, 12 basic and clinical departments at CWRU, and 3 affiliated hospitals. The VSRC has an already established and excellent basic science research program as evidenced by 17 current R01 and R03 awards, a P30 Core Grant and T32 Training Grant. The next goal of the VSRC is to expand and strengthen resources to establish a strong clinical vision research program. This R21 award will allow for the expansion of the VSRC Clinical Research Unit and the creation of a VSRC Biostatistics Unit, two resources critical to the continued development of clinical vision research at CWRU. Under the direction of Jonathan Lass, M.D., PI of this proposed project and the current P30 Core Grant, Director of the VSRC, and Chairman of the CWRU Department of Ophthalmology, our specific aims are as follows: 1) expand the resources, knowledge, and staff of our existing Clinical Research Unit, 2) establish a Biostatistics Unit which will be self sufficient in serving all the study design, data analysis, and data reporting needs of our clinical investigators, and 3) ultimately establish data coordinating center capabilities and activities. Together with a strong basic science program and an expanding clinical science program made possible through this R21 award, we seek to place the CWRU VSRC as one of the leading visual sciences research centers in this country.

该R21临床视觉研究开发奖旨在提高凯斯西储大学视觉科学研究中心（VSRC）研究人员的临床研究活动和能力。CWRU VSRC位于眼科，包括30多名视觉科学研究人员，CWRU的12个基础和临床部门以及3家附属医院。该VSRC已经建立和优秀的基础科学研究计划，证明了17个当前的R01和R03奖项，一个P30核心补助金和T32培训补助金。VSRC的下一个目标是扩大和加强资源，以建立一个强大的临床视觉研究计划。该R21奖项将允许扩展VSRC临床研究单位和创建VSRC生物统计单位，这两个资源对CWRU临床视觉研究的持续发展至关重要。 在医学博士乔纳森·拉斯的指导下，这个拟议项目的PI和目前的P30核心补助金，VSRC主任和CWRU眼科系主任，我们的具体目标如下：1）扩大我们现有临床研究部门的资源、知识和人员，2）建立一个生物统计部门，该部门将自给自足，满足我们临床研究者的所有研究设计、数据分析和数据报告需求，以及3）最终建立数据协调中心能力和活动。通过这项R21奖，我们提供了强大的基础科学项目和不断扩大的临床科学项目，我们希望将CWRU VSRC作为该国领先的视觉科学研究中心之一。

项目成果

Predictive factors for corneal infiltrates with continuous wear of silicone hydrogel contact lenses.

• DOI: 10.1001/archopht.125.4.488
• 发表时间: 2007-04
• 期刊: Archives of ophthalmology
• 作者: L. Szczotka-Flynn;S. Debanne;V. Cheruvu;B. Long;S. Dillehay;J. Barr;P. Bergenske;P. Donshik

Descemet's stripping automated endothelial keratoplasty: three-year graft and endothelial cell survival compared with penetrating keratoplasty.

• DOI: 10.1016/j.ophtha.2012.08.007
• 发表时间: 2013-02
• 期刊: Ophthalmology
• 影响因子: 13.7
• 作者: Price MO;Gorovoy M;Price FW Jr;Benetz BA;Menegay HJ;Lass JH
• 通讯作者: Lass JH