CORE--ENVIRONMENTAL EFFECTS ON SIGNAL TRANSDUCTION

核心--环境对信号传导的影响

基本信息

项目摘要

Description (provided by applicant): A wide range of toxicants and drugs exert their biological actions by interfering with cell?cell and intracellular signaling pathways. These agents either mimic a signaling molecule or alter a signaling pathway in such a way as to lead to toxicity. The purpose of the Signal Transduction Core is to bring together investigators with common interests in understanding how xenobiotics modulate cellular signal transduction pathways. The aim of the Signal Transduction Core is to provide a platform for investigators with common interest in exploring the role of altered cellular signal transduction pathways in toxicant mechanisms. The core is under the direction of Dr. Jeffrey D. Laskin and is co-directed by Dr. Marion K. Gordon. There are 16 core members from several different departments at RWJMS and Rutgers University. The core functions as a mechanism to keep members current with respect to new developments in signal transduction and to provide a forum for meaningful scientific interaction at both the didactic and laboratory levels. The future goals of the core are to develop a toxicoinformatics program to support member research projects, which could benefit from computational assistance. In addition, the core will continue to recruit new investigators, submit grant applications and organize technology-based workshops.
描述(由申请人提供): 多种毒物和药物通过干扰细胞、细胞和细胞内信号传导途径发挥其生物作用。这些药物要么模仿信号分子,要么改变信号通路从而导致毒性。信号转导的目的 核心是将具有共同兴趣的研究人员聚集在一起,了解异生素如何 调节细胞信号转导途径。 信号转导核心的目的是为有共同兴趣探索改变的细胞信号转导途径在毒物机制中的作用的研究人员提供一个平台。该核心由 Jeffrey D. Laskin 博士指导,并由 Marion K. Gordon 博士共同指导。核心成员有 16 名,分别来自 RWJMS 和罗格斯大学的多个不同部门。该核心功能是一种机制,使成员了解信号转导的新发展,并为教学和学术领域有意义的科学互动提供论坛。 实验室水平。该核心的未来目标是开发一个毒物信息学计划来支持成员研究项目,该项目可以从计算辅助中受益。此外,核心将继续招募新的研究人员、提交资助申请并组织基于技术的研讨会。

项目成果

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JEFFREY D LASKIN其他文献

JEFFREY D LASKIN的其他文献

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{{ truncateString('JEFFREY D LASKIN', 18)}}的其他基金

Advanced Development of Drugs to Mitigate Parathion Intoxication
减轻对硫磷中毒药物的先进开发
  • 批准号:
    10000186
  • 财政年份:
    2018
  • 资助金额:
    $ 8.63万
  • 项目类别:
Advanced Development of Drugs to Mitigate Parathion Intoxication
减轻对硫磷中毒药物的先进开发
  • 批准号:
    10227007
  • 财政年份:
    2018
  • 资助金额:
    $ 8.63万
  • 项目类别:
Advanced Development of Drugs to Mitigate Parathion Intoxication
减轻对硫磷中毒药物的先进开发
  • 批准号:
    10471251
  • 财政年份:
    2018
  • 资助金额:
    $ 8.63万
  • 项目类别:
Developing Drugs to Mitigate Parathion Intoxication
开发减轻对硫磷中毒的药物
  • 批准号:
    8545998
  • 财政年份:
    2013
  • 资助金额:
    $ 8.63万
  • 项目类别:
Developing Drugs to Mitigate Parathion Intoxication
开发减轻对硫磷中毒的药物
  • 批准号:
    8735201
  • 财政年份:
    2013
  • 资助金额:
    $ 8.63万
  • 项目类别:
"Development of Drugs to Mitigate Parathion Intoxication"
“开发减轻对硫磷中毒的药物”
  • 批准号:
    8019746
  • 财政年份:
    2010
  • 资助金额:
    $ 8.63万
  • 项目类别:
"Development of Drugs to Mitigate Parathion Intoxication"
“开发减轻对硫磷中毒的药物”
  • 批准号:
    8548459
  • 财政年份:
    2010
  • 资助金额:
    $ 8.63万
  • 项目类别:
"Development of Drugs to Mitigate Parathion Intoxication"
“开发减轻对硫磷中毒的药物”
  • 批准号:
    8153112
  • 财政年份:
    2010
  • 资助金额:
    $ 8.63万
  • 项目类别:
TOXICOLOGY MODULE
毒理学模块
  • 批准号:
    7953846
  • 财政年份:
    2008
  • 资助金额:
    $ 8.63万
  • 项目类别:
ENVIRONMENTAL EFFECTS ON SIGNAL TRANSDUCTION
环境对信号传导的影响
  • 批准号:
    7953841
  • 财政年份:
    2008
  • 资助金额:
    $ 8.63万
  • 项目类别:

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