Optical Biology Core

光学生物学核心

• 批准号: 7432210
• 负责人: ENRICO GRATTON
• 金额: $ 82.02万
• 依托单位: UNIVERSITY OF CALIFORNIA-IRVINE
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-07-01 至 2012-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7432210
• 关键词: Behavior; Biological; Biology; Collection; Computer software; Development; Diffusion; Equipment; Faculty; Fluorescence; Goals; Human Resources; Image; Label; Microscopy; Monitor; Optics; Organism; Preparation; Research Personnel; Resolution; Running; Scanning; Specimen; System; Techniques; Technology; Thinking; image processing; improved; in vivo; particle; tool; tool development

Theme E. Optical Biology: Improved Tools for in vivo Observation and Quantification Theme Leader: Gratton. Other Project Faculty: Marsh, Gross Overview of the Optical Biology Core This Center is concerned with spatial dynamics at many levels. Recent improvements in microscopy technology, probe development, image processing software, and specimen preparation have now made it possible to monitor dynamic behaviors in biological systems with a degree of sensitivity and resolution once thought impossible. The great hurdle now is useful quantification of the information we can obtain in the form of images. The goal of the CCBS Optical Biology Core is to develop, apply, and make available microscopy techniques for quantifying spatial dynamics in living systems. To this end, the core is not simply a collection of equipment and personnel to help keep things running. It consists of specific tool application and tool development projects, led by Center investigators.

主题 E. 光学生物学：改进的工具 体内观察和定量 主题负责人：格拉顿。 其他项目教师：Marsh、Gross 光学生物学核心概述 该中心关注多个层面的空间动态。显微镜的最新改进 技术、探针开发、图像处理软件和样品制备现已取得 可以以一定程度的灵敏度和分辨率监测生物系统的动态行为 一度认为不可能。现在最大的障碍是对我们可以获得的信息进行有用的量化 以图像的形式。 CCBS 光学生物学核心的目标是开发、应用和制造 用于量化生命系统空间动力学的可用显微镜技术。为此， 核心不仅仅是帮助保持事物运行的设备和人员的集合。 它由由中心研究人员领导的特定工具应用和工具开发项目组成。