FLUORESCENCE LIFETIME IMAGING MICROSCOPY OF BIOSENSORS

生物传感器的荧光寿命成像显微镜

• 批准号: 8365768
• 负责人: ENRICO GRATTON
• 金额: $ 7.02万
• 依托单位: UNIVERSITY OF CALIFORNIA-IRVINE
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-08-20 至 2012-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8365768
• 关键词: Biosensor; Cells; Fluorescence; Funding; Grant; Guanosine Triphosphate Phosphohydrolases; Image; Laboratories; Life; Measures; Microscopy; National Center for Research Resources; North Carolina; Principal Investigator; Proteins; Research; Research Infrastructure; Resources; Source; United States National Institutes of Health; Universities; cost; rho

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. We are measuring the lifetime of fluorescecnce biosensors in live cells. This in colloboration with Dr. Klaus Hahn at the University of North Carolina, Chapel-Hill. The biosensors detect GTPase activation including Rac and Rho proteins.

该子项目是利用资源的众多研究子项目之一 由 NIH/NCRR 资助的中心拨款提供。子项目的主要支持 并且子项目的主要研究者可能是由其他来源提供的， 包括其他 NIH 来源。 子项目可能列出的总成本 代表子项目使用的中心基础设施的估计数量， NCRR 赠款不直接向子项目或子项目工作人员提供资金。 我们正在测量活细胞中荧光生物传感器的寿命。这是与北卡罗来纳大学教堂山分校的 Klaus Hahn 博士合作完成的。生物传感器检测 GTP 酶激活，包括 Rac 和 Rho 蛋白。