Formaldehyde Molecular Recognition Microsensor

甲醛分子识别微传感器

• 批准号: 7480066
• 负责人: Oleg G. Polyakov
• 金额: $ 9.82万
• 依托单位: SYNKERA TECHNOLOGIES, INC.
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-05-15 至 2010-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7480066
• 关键词: Address; Air; Aluminum Oxide; Architecture; Area; Benzene; Biomedical Engineering; Chemicals; Chemistry; Condition; Deposition; Detection; Development; Electronics; Elements; Ensure; Environmental Health; Environmental air flow; Evaluation; Exposure to; Family; Formaldehyde; Government; Health; Health protection; Human; Indoor Air Quality; Institutes; Letters; Measures; Methods; Microfabrication; Mission; Monitor; NIH Program Announcements; Nanotechnology; Operative Surgical Procedures; Organic Chemicals; Pattern; Performance; Persons; Phase; Production; Public Health; Purpose; Quality Control; Range; Recovery; Relative (related person); Research; Research Design; Research Project Grants; Secure; Shapes; Simulate; Small Business Innovation Research Grant; Stream; Structure; Surface; System; Technology; Testing; Time; Water; air contaminant; commercialization; cost; design; exposed human population; instrumentation; molecular recognition; nanometer; nanoscale; nanostructured; novel; performance tests; prototype; response; sensor; small molecule; solid state; stannic oxide; toxicant; vapor

DESCRIPTION (provided by applicant): This three-phase Small Business Innovation Research project addresses one the most significant problems in public health protection: monitoring of indoor air quality and controlling the ventilation systems in residential, office and industrial buildings. The development of a novel advanced microsensor for detecting gaseous formaldehyde in air is proposed. The sensing method utilizes the conductivity change induced, upon exposure to formaldehyde, in a layer of tin oxide. Cross-sensitivity to other volatile organic chemicals is eliminated by patterning of the tin oxide surface by an inert protecting layer with sub-nanometer pores, each shaped to selectively host a single formaldehyde molecule. Incorporation of this novel sensing material into a high-area nanostructured sensor platform will enable production of highly sensitive, selective, low-power, and low-cost formaldehyde microsensors. The Phase I project will demonstrate the feasibility of the proposed approach through fabrication of sensors and their comprehensive testing in conditions simulating contaminated indoor air. To ensure successful Phase II product development and Phase III commercialization, partnership has been secured with one of the leading developers of components and systems for energy applications. By combining coordination chemistry with nanotechnology and microfabrication, the proposed approach is likely to enable a novel family of low-cost highly sensitive and selective sensor systems for precise quantitative monitoring of human exposures to toxicants. Thus, the proposed research is highly relevant to the mission of the National Institute Of Environmental Health Sciences. Public Health Relevance: The project addresses one the most significant problems in public health protection: monitoring of indoor air quality and controlling the ventilation systems in residential, office, and industrial buildings. The development of novel advanced sensors for detecting formaldehyde - one of the most ubiquitous and dangerous for human health air contaminants - is proposed. The proposed technology will enable a novel family of high-performance and low-cost sensor systems for generating precise and quantitative measures of human exposure to harmful chemicals at the point of contact.

描述（由申请人提供）：这个三阶段的小型企业创新研究项目解决了公共卫生保护中最重要的问题之一：监测住宅、办公和工业建筑的室内空气质量和控制通风系统。提出开发一种用于检测空气中气态甲醛的新型先进微传感器。该传感方法利用氧化锡层暴露于甲醛时引起的电导率变化。通过具有亚纳米孔的惰性保护层对氧化锡表面进行图案化，可以消除对其他挥发性有机化学品的交叉敏感性，每个孔的形状可以选择性地容纳单个甲醛分子。 将这种新型传感材料纳入大面积纳米结构传感器平台将能够生产高灵敏度、选择性、低功耗和低成本的甲醛微传感器。第一阶段项目将通过制造传感器并在模拟受污染的室内空气条件下进行全面测试来证明所提出方法的可行性。为了确保第二阶段产品开发和第三阶段商业化的成功，我们与能源应用组件和系统的领先开发商之一建立了合作伙伴关系。 通过将配位化学与纳米技术和微加工相结合，所提出的方法可能会实现一系列新型低成本高灵敏度和选择性传感器系统，用于精确定量监测人类接触有毒物质的情况。因此，拟议的研究与国家环境健康科学研究所的使命高度相关。 公共卫生相关性：该项目解决了公共卫生保护中最重要的问题之一：监测住宅、办公室和工业建筑的室内空气质量和控制通风系统。建议开发用于检测甲醛（对人类健康最普遍且最危险的空气污染物之一）的新型先进传感器。拟议的技术将使一系列新型高性能和低成本传感器系统成为可能，用于对人体在接触点接触有害化学物质的情况进行精确和定量的测量。