AR CAREER DEVELOPMENT COBRE: ADMINISTRATIVE CORE

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 描述(由申请人提供)： 我们为五名接近国家竞争力水平的项目调查员实施了职业发展计划，利用现有调查员提供的赠款支持和指导活动。每个项目都涉及独特的、创新的最先进的研究。目标是帮助这些PI在1-3年内获得导师资助或R01资金，用其他接近全国竞争水平的调查人员取代他们，并帮助这些调查人员获得外部支持。到颁奖期结束时，我们的目标是1)为至少7名新研究员产生导师资助和R01资金，以及2)获得另外两个多研究员奖项。所选择的项目具有显著的协同效应，这将有助于实现第三个目标：3)提交一份计划项目申请(P01)，将至少三名新的R01获奖者与其他现有的调查人员联系起来。我们已经建立了一个多学科的翻译神经科学中心(CTN)，该中心利用现有的教员优势，扩大神经科学研究基础设施，成为校园范围内合作的中心。CTN正在受益于招募终身教职、资助的调查人员，他们已经成为项目绩效指标的导师。在该奖项的有效期内，还将招聘另外三名教师，以增加调查人员的临界数量。通过试点研究奖励计划，已经招募了另外两名潜在的未来绩效评估人员。这一努力的重大机构承诺将在授权期结束时转化为对中心的独立外部支持(P50奖)。CTN主任在大型发展计划、计划项目赠款方面有经验，并已由联邦政府资助20多年。我们已经建立了两个核心设施，一个是行政核心，另一个是实验核心，以提供有效的手段，确保训练有素的专业人员充分使用、维护和操作复杂而昂贵的仪器。我们将确保PIs项目能够获得最先进的服务和设施(通过每年购买新设备)，为UAMS的翻译神经科学研究工作提供基本基础。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. DESCRIPTION (provided by applicant): We implemented a Career Development Program for five Project Investigators (PIs) who are close to nationally competitive levels using grant support and mentoring activities undertaken by established investigators. Each Project involves unique, innovative state-of-the-art research. The goal is to help these PIs secure mentored grants or R01 funding within 1-3 years, replacing them with other investigators close to nationally competitive levels, and helping those investigators secure extramural support. By the end of the award period, our goals are 1) to generate mentored grants and R01 funding for at least seven new investigators, and 2) to secure two additional multi-investigator awards. The Projects chosen have significant synergy, which will facilitate the third goal, 3) the submission of a Program Project application (P01) linking at least three of the new R01 awardees with other established investigators. We have established a multi-disciplinary Center for Translational Neuroscience (CTN) that takes advantage of the existing faculty strengths and expand the neuroscience research infrastructure, becoming a hub for campuswide collaborations. The CTN is benefitting from the recruitment of tenure-track, funded investigators who have become mentors to Project PIs. Three other faculty will be recruited during the life of the award, adding to the critical mass of investigators. Two additional potential future PIs have been recruited through a Pilot Study award program. The significant institutional commitment for this effort, will be parlayed into independent extramural support for the Center (P50 award) by the end of the award period. The Director of the CTN has experience with large-scale development programs, Program Project grants and has been Federally funded for over 20 years. We have established two Core Facilities, an Administrative and an Experimental Core, to provide an efficient means of ensuring that sophisticated and expensive instrumentation is fully utilized, maintained and operated by trained professionals. We will ensure that Project PIs have access to state-of-the-art services and facilities (through yearly purchases of new equipment), providing the basic underpinnings of the translational neuroscience research efforts at UAMS.