7 TESLA TECHNOLOGY FOR FUNCTIONAL IMAGING

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 西门子医疗解决方案在过去的7年里一直与MGH合作开发高场(7T)MRI技术，用于大脑的研究应用。MGH系统被安装为开发这项技术的原型和试验台。西门子有3名现场工程师为MGH的这个项目和其他项目提供便利，并在Erlangen的工厂有一名7T项目经理。获得西门子的设备、制造能力和专业知识对MGH来说是无价的，因为它成功地使该系统运行并优化了其性能。7Tesla技术对所有相关人员来说仍然是相对较新的技术；目前还没有已知的可以直接发货的“最佳配置”。例如，我们资源的项目2评估了大多数重要子系统的多次迭代。我们使用了3种不同的磁头梯度，2种不同类型的配置，2种不同的射频接收器版本，以及无数的射频线圈。与西门子的合作对于确保该系统针对所需的功能成像应用进行优化至关重要。 阵列技术合作的中心是开发目前安装在MGH 3T系统上的128通道接收器系统。当资源准备好使用时，该系统将在MGH 7T系统上复制。MGH将负责提供和安装前置放大器阵列和第二级放大器。西门子-MGH大阵列线圈的合作已经使1.5T和3T 32通道脑阵列成为商业产品。西门子对更高元素计数的早期经验为西门子提供了对这一方向的效用的早期看法。同样，西门子对广义模式混合问题也很感兴趣；当前的“TIM”平台使用巴特勒矩阵的3x3等效项作为模式混合策略。这种方法的成功激发了人们对其他更大规模的模式混合方案的浓厚兴趣。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Siemens Medical Solutions has been working with the MGH for the past 7 years to develop high field (7T) MRI technology for research applications of the brain. The MGH system was installed as a prototype and test-bed for developing this technology. Siemens has dedicated 3 on-site engineers to facilitate this and other projects at the MGH and has a 7T project manager at the factory in Erlangen. Access to equipment, manufacturing ability and expertise at Siemens has been invaluable to MGH for successfully getting this system running and optimizing its performance. Seven Tesla technology is still relatively new for all involved; there is no known "optimal configuration" that can just be shipped. For example, Project 2 of our Resource has evaluated multiple iterations of most of the important sub-systems. We have utilized 3 different head gradients, 2 different types configurations, 2 different RF receiver incarnations, and countless RF coils. The collaboration with Siemens has been crucial for ensuring that this system is optimized for the functional imaging applications desired. The array technology collaboration centers around developing the 128-channel receiver system currently in place on the MGH 3T system. This system will be duplicated on the MGH 7T system when the recourse is ready to utilize it. MGH will be responsible for providing and installing the preamplifier array and second stage amplifiers. The Siemens-MGH large array coil collaboration has already lead to a 1.5T and 3T 32 channel brain array as a commercial product. The early experience into even higher element counts provides Siemens with an early view of the utility of this direction. Similarly, the generalized mode-mixing problem is of interest to Siemens; the current "TIM" platform utilizes a 3x3 equivalent of the Butler matrix as a mode-mixing strategies. The success of this methodology spurs keen interest in other, larger-scale, mode mixing schemes.