IMAGING RESEARCH CORE

影像研究核心

• 批准号: 7529365
• 负责人: JEFFREY L. DUERK
• 金额: $ 12.64万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-07-06 至 2012-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7529365
• 关键词: Academic Training; Agreement; Animal Disease Models; Animals; Arts; Basic Science; Biomedical Engineering; Cancer Center; Clinic; Clinical; Collaborations; Complex; Comprehensive Cancer Center; Core Facility; Developmental Therapeutics Program; Disease; Faculty; Genetic Structures; Hospitals; Image; Laboratories; Link; Malignant Neoplasms; Measurement; Medical Students; Microscopic; Mission; Molecular; Patient Care; Physiological; Physiology; Purpose; Radiology Specialty; Regional Cancer; Research; Research Infrastructure; Research Institute; Research Personnel; Resources; Schools; Services; Small Animal Imaging Systems; Structure; Technology; Therapeutic; Universities; University Hospitals; anticancer research; base; in vivo; molecular imaging; pre-clinical; programs

The Imaging Research Core Facility provides researchers with the state-of-the art facilities and services for in vivo imaging. The facility provides cancer researchers its extensive imaging research infrastructure and expertise of -15 imaging faculty in Radiology and Biomedical Engineering to enhance and expand their ongoing research efforts. The advent of dedicated small animal imaging systems allows the integration of in vivo physiologic measurements with microscopic measurements of structural and cellular activities. The collaborative, multi-disciplinary approach provides a wealth of new information in elucidating the complex relationship between structure, genetics, replication, and function in genetically manipulated animal models of disease that have been used widely in cancer research with grounding in cellular/molecular-level understanding. The Imaging Research Core Facility is the centerpiece of the Case Center for Imaging Research which encompasses all aspects of the much broader imaging research program at Case/UHC. This includes molecular imaging, small animal imaging, and clinical imaging thrusts. Many of these thrusts are directly tied to the Case Comprehensive Cancer Center (Case CCC). The Imaging Research Core Facility's molecular and small animal imaging services, technologies, and research programs are described in detail below. Clinical imaging research programs are described in more detail in the Program 7: Developmental Therapeutics proposal.

成像研究核心设施为研究人员提供了最先进的设施和服务 体内成像。该设施为癌症研究人员提供了广泛的成像研究基础设施和 -15放射学和生物医学工程学院的专业知识，以增强和扩展其 正在进行的研究工作。专用的小动物成像系统的出现允许集成 结构和细胞活性的微观测量，体内生理测量。这 协作，多学科的方法为阐明复合物提供了大量的新信息 结构，遗传学，复制和功能之间的关系在遗传操纵的动物模型中 在癌症研究中广泛使用的疾病，在细胞/分子水平中接地 理解。成像研究核心设施是案例成像中心的核心 研究涵盖了CASE/UHC上更广泛的成像研究计划的各个方面。 这包括分子成像，小动物成像和临床成像推力。其中许多推力 直接与病例综合癌症中心（CASE CCC）绑定。成像研究核心 描述了设施的分子和小动物成像服务，技术和研究计划 在下面的详细信息中。临床成像研究计划在计划7中更详细地描述了： 发育治疗建议。