IMAGING RESEARCH CORE

影像研究核心

• 批准号: 7529365
• 负责人: JEFFREY L. DUERK
• 金额: $ 12.64万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-07-06 至 2012-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7529365
• 关键词: Academic Training; Agreement; Animal Disease Models; Animals; Arts; Basic Science; Biomedical Engineering; Cancer Center; Clinic; Clinical; Collaborations; Complex; Comprehensive Cancer Center; Core Facility; Developmental Therapeutics Program; Disease; Faculty; Genetic Structures; Hospitals; Image; Laboratories; Link; Malignant Neoplasms; Measurement; Medical Students; Microscopic; Mission; Molecular; Patient Care; Physiological; Physiology; Purpose; Radiology Specialty; Regional Cancer; Research; Research Infrastructure; Research Institute; Research Personnel; Resources; Schools; Services; Small Animal Imaging Systems; Structure; Technology; Therapeutic; Universities; University Hospitals; anticancer research; base; in vivo; molecular imaging; pre-clinical; programs

The Imaging Research Core Facility provides researchers with the state-of-the art facilities and services for in vivo imaging. The facility provides cancer researchers its extensive imaging research infrastructure and expertise of -15 imaging faculty in Radiology and Biomedical Engineering to enhance and expand their ongoing research efforts. The advent of dedicated small animal imaging systems allows the integration of in vivo physiologic measurements with microscopic measurements of structural and cellular activities. The collaborative, multi-disciplinary approach provides a wealth of new information in elucidating the complex relationship between structure, genetics, replication, and function in genetically manipulated animal models of disease that have been used widely in cancer research with grounding in cellular/molecular-level understanding. The Imaging Research Core Facility is the centerpiece of the Case Center for Imaging Research which encompasses all aspects of the much broader imaging research program at Case/UHC. This includes molecular imaging, small animal imaging, and clinical imaging thrusts. Many of these thrusts are directly tied to the Case Comprehensive Cancer Center (Case CCC). The Imaging Research Core Facility's molecular and small animal imaging services, technologies, and research programs are described in detail below. Clinical imaging research programs are described in more detail in the Program 7: Developmental Therapeutics proposal.

成像研究核心设施为研究人员提供最先进的设施和服务， 体内成像。该设施为癌症研究人员提供了广泛的成像研究基础设施， 放射学和生物医学工程方面的专业知识，以加强和扩大他们的 正在进行的研究工作。专用的小动物成像系统的出现允许将 体内生理测量与结构和细胞活性的显微测量。的 合作，多学科的方法提供了丰富的新信息，阐明复杂的 基因操作动物模型中结构、遗传、复制和功能之间的关系 在细胞/分子水平上， 认识成像研究核心设施是成像案例中心的核心 研究涵盖了Case/UHC更广泛的成像研究计划的各个方面。 这包括分子成像、小动物成像和临床成像。许多这样的推力 Case Comprehensive Cancer Center（Case CCC）影像研究核心 设施的分子和小动物成像服务，技术和研究计划进行了说明 下面详细描述。临床影像学研究项目在项目7中有更详细的描述： 发展治疗学提案。