Identification of novel epigenetic modifiers involved in neural stem cell function and glioblastoma

大脑是由干细胞产生的，这些干细胞有能力在发育过程中和受伤后生成大脑中的所有成熟细胞。脑干细胞具有改变再生医学或治疗神经退行性疾病的功能的治疗潜力，因此引起了人们的兴趣。这些干细胞还具有与脑瘤细胞相同的特征。我们寻求识别在脑干细胞和脑瘤中重要的基因，以便识别新的治疗靶点。

The brain is produced from stem cells that have the capacity to make all the mature cells in the brain, both during development, and after injury. Brain stem cells are of interest due to the therapeutic potential to alter their function for regenerative medicine or treatment of neurodegenerative disorders. These stem cells also have characteristics in common with brain tumour cells. We seek to identify genes important in brain stem cells and brain tumours, in order to identify new targets for therapy.