Identification of novel HCV-specific B cell epitopes which induce broad neutralising antibodies

鉴定可诱导广泛中和抗体的新型 HCV 特异性 B 细胞表位

• 批准号: nhmrc : 1080307
• 负责人: A/Pr Fabio Luciani
• 金额: $ 32.17万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/identification-novel-hcv-neutralising-antibodies/518736
• 关键词: Identification; novel; HCV; specific; cell

This research project will study humans who have been exposed to multiple Hepatitis C virus infections. We will be examining their immune response with the aim to identify subjects with antibodies that are able to neutralise a diverse range of hepatitis C virus variants. These antibodies will be used to identify novel targets for a vaccine directed against Hepatitis C virus.

这项研究项目将研究接触过多种丙型肝炎病毒感染的人类。我们将检查他们的免疫反应，目的是识别具有能够中和多种丙型肝炎病毒变异株的抗体的受试者。这些抗体将被用于识别针对丙型肝炎病毒的疫苗的新靶点。