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Determining the unique processes that control memory B cell-mediated secondary antibody responses

Determining the unique processes that control memory B cell-mediated secondary antibody responses
确定控制记忆 B 细胞介导的二抗反应的独特过程
批准号:
nhmrc : 1124681
负责人:
A/Pr Fabio Luciani
金额:
$58.34万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2017
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2017-01-01 至 2020-12-31

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中文摘要
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英文摘要
Vaccines educate the immune system by training memory cells to make neutralizing antibodies when it re-encounters the pathogen. However, where and how these memory cells are activated in the secondary antibody response in immune animals remain unknown. Here we use cutting edge technologies to fate map and gene profile memory cells and determine the molecular switches that control the secondary antibody response. This will be complemented by human vaccine studies.
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会议论文
Systems immunology of antigen specific T cells: from single-cell to immune protection
  • 批准号:
    nhmrc : 1128416
  • 项目类别:
    Career Development Fellowships
  • 资助金额:
    $32.12万
  • 财政年份:
    2017
  • 负责人:
    A/Pr Fabio Luciani
  • 依托单位:
Determining the unique processes that control memory B cell-mediated secondary antibody responses
  • 批准号:
    nhmrc : GNT1124681
  • 项目类别:
    Project Grants
  • 资助金额:
    $85.36万
  • 财政年份:
    2017
  • 负责人:
    A/Pr Fabio Luciani
  • 依托单位:
The phenotype of protective cytotoxic T cell responses during viral infections
  • 批准号:
    nhmrc : GNT1121643
  • 项目类别:
    Project Grants
  • 资助金额:
    $84.11万
  • 财政年份:
    2017
  • 负责人:
    A/Pr Fabio Luciani
  • 依托单位:
The phenotype of protective cytotoxic T cell responses during viral infections
  • 批准号:
    nhmrc : 1121643
  • 项目类别:
    Project Grants
  • 资助金额:
    $57.49万
  • 财政年份:
    2017
  • 负责人:
    A/Pr Fabio Luciani
  • 依托单位:
国内基金
海外基金
微分动力系统的测度和熵
  • 批准号:
    11101447
  • 项目类别:
    青年科学基金项目
  • 资助金额:
    22.0万元
  • 批准年份:
    2011
  • 负责人:
    孙鹏
  • 依托单位: