Determining the unique processes that control memory B cell-mediated secondary antibody responses
Determining the unique processes that control memory B cell-mediated secondary antibody responses
批准号:
nhmrc : 1124681
负责人:
A/Pr Fabio Luciani
金额:
$58.34万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2017
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2017-01-01 至 2020-12-31
中文摘要
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英文摘要
Vaccines educate the immune system by training memory cells to make neutralizing antibodies when it re-encounters the pathogen. However, where and how these memory cells are activated in the secondary antibody response in immune animals remain unknown. Here we use cutting edge technologies to fate map and gene profile memory cells and determine the molecular switches that control the secondary antibody response. This will be complemented by human vaccine studies.
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会议论文
Systems immunology of antigen specific T cells: from single-cell to immune protection
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批准号:nhmrc : 1128416
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负责人:A/Pr Fabio Luciani
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依托单位:
Determining the unique processes that control memory B cell-mediated secondary antibody responses
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负责人:A/Pr Fabio Luciani
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依托单位:
The phenotype of protective cytotoxic T cell responses during viral infections
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负责人:A/Pr Fabio Luciani
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依托单位:
Systems immunology of antigen specific T cells: from single-cell to immune protection
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资助金额:$47.01万
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依托单位:
Virological determinants of drug resistance in real-world patients with chronic HCV infection
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Novel bioinformatic methods to study genomic complexity in liver disease
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依托单位:
Novel bioinformatic methods to determine the link between genomic complexity of hepatitis viruses and liver disease phenotypes
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批准号:nhmrc : 1060199
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资助金额:$40.4万
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负责人:A/Pr Fabio Luciani
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依托单位:
HCV founder viruses as vaccine targets
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Prevention and treatment of viral hepatitis amongst prisoners
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财政年份:2011
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负责人:A/Pr Fabio Luciani
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依托单位:
Modelling the evolution of Hepatitis C virus by integrating large sequence- and immunological-databases.
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依托单位:
国内基金
海外基金
微分动力系统的测度和熵
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批准号:11101447
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批准年份:2011
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负责人:孙鹏
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依托单位: