Identification of novel gonococcal virulence factors and vaccine antigens based on their expression during host cell contact and their role in association, invasion and survival in cervical epithelia
Identification of novel gonococcal virulence factors and vaccine antigens based on their expression during host cell contact and their role in association, invasion and survival in cervical epithelia
批准号:
nhmrc : 1028326
负责人:
A/Pr Kate Seib
金额:
$24.8万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2012
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2012-01-01 至 2016-12-31
中文摘要
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英文摘要
The sexually transmitted infection gonorrhoea is a significant health problem worldwide. Control of gonorrhoea depends on the development of a vaccine due to the continuing increase of antibiotic resistance and the staggering outcomes of infection, including infertility and increased transmission of HIV. My research aims to discover new vaccine targets by identifying gonococcal proteins that are required for interaction with human cervical cells.
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Developing species-specific, structure-targeting peptides as a novel class of antibiotics
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批准号:nhmrc : GNT1121629
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项目类别:Project Grants
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资助金额:$60.8万
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财政年份:2017
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负责人:A/Pr Kate Seib
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依托单位:
Developing species-specific, structure-targeting peptides as a novel class of antibiotics
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批准号:nhmrc : 1121629
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项目类别:Project Grants
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资助金额:$41.49万
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财政年份:2017
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负责人:A/Pr Kate Seib
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依托单位:
The glyco-interactome of pathogenic Neisseria: understanding disease and defining vaccine targets
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批准号:nhmrc : 1099278
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项目类别:Project Grants
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资助金额:$29.55万
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财政年份:2016
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负责人:A/Pr Kate Seib
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依托单位:
Novel epigenetic regulatory mechanisms in Moraxella catarrhalis and non-typeable Haemophilus influenzae: impact on vaccine development and role in pathobiology
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批准号:nhmrc : GNT1099279
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项目类别:Project Grants
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资助金额:$62.7万
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财政年份:2016
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负责人:A/Pr Kate Seib
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依托单位:
Novel epigenetic regulatory mechanisms in Moraxella catarrhalis and non-typeable Haemophilus influenzae: impact on vaccine development and role in pathobiology
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批准号:nhmrc : 1099279
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项目类别:Project Grants
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资助金额:$42.99万
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财政年份:2016
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负责人:A/Pr Kate Seib
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依托单位:
The glyco-interactome of pathogenic Neisseria: understanding disease and defining vaccine targets
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批准号:nhmrc : GNT1099278
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项目类别:Project Grants
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资助金额:$43.1万
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财政年份:2016
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负责人:A/Pr Kate Seib
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依托单位:
Vaccine discovery for human mucosal pathogens: identifying novel vaccine antigens that are stably expressed during host interactions, using analysis of cell-contact and phasevarion mediated expression profiles
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批准号:nhmrc : 1045235
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项目类别:Career Development Fellowships
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资助金额:$27.9万
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财政年份:2013
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负责人:A/Pr Kate Seib
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依托单位:
Role in disease of a novel epigenetic regulator associated with the hypervirulent Neisseria meningitidis clonal complex 41/44
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批准号:nhmrc : 1021631
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项目类别:Project Grants
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资助金额:$26.89万
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财政年份:2012
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负责人:A/Pr Kate Seib
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依托单位:
Characterisation of Neisseria meningitidis vaccine candidates
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批准号:nhmrc : 456152
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项目类别:Early Career Fellowships
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资助金额:$21.74万
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财政年份:2007
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负责人:A/Pr Kate Seib
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依托单位:
国内基金
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