Mechanochemical Effects on Tumor Cell Signaling, Adhersion and Migration

机械化学对肿瘤细胞信号传导、粘附和迁移的影响

• 批准号: 7812875
• 负责人: Konstantinos Konstantopoulos
• 金额: $ 36.18万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-01 至 2014-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7812875
• 关键词: Actins; Adhesions; Adhesiveness; Affinity; Antibodies; Apoptotic; Avidity; Binding; Biological Assay; Blood Cells; CD44 gene; Cadherins; Cell Adhesion Molecules; Cell Cycle; Cell Line; Cell physiology; Cell-Cell Adhesion; Cells; Chemicals; Chondrocytes; Colon Carcinoma; Computing Methodologies; Confined Spaces; Coupled; Endothelial Cells; Enrollment; Enzymes; Extracellular Matrix; Extravasation; Fibrin; Fluorescence Microscopy; Generations; Genes; Genomics; Goals; Hyaluronic Acid; Hypoxia; Image; Integrins; Intercellular Fluid; Kinetics; Ligand Binding; Ligands; Malignant neoplasm of pancreas; Mass Spectrum Analysis; Mechanical Stress; Mechanics; Mediating; Metabolic; Methods; Microfabrication; Modeling; Monitor; Monomeric GTP-Binding Proteins; Neoplasm Metastasis; Oxygen measurement, partial pressure, arterial; Pathway interactions; Pattern; Pharmacia brand of estropipate; Physics; Polysaccharides; Primary Neoplasm; Process; Property; Protein Isoforms; Proteins; Proteomics; Quantum Dots; RNA; RNA Interference; Radioimmunoconjugate; Receptor Cell; Regulation; Relative (related person); Research; Resistance; Resources; Risk; Role; Selectins; Signal Transduction; Simulate; Spectrum Analysis; Stimulus; Structure; Students; Surface; Testing; Training Programs; Treatment Failure; Tumor Tissue; Variant; Width; base; cancer cell; cell growth; cell motility; computer studies; density; experience; fluid flow; glycosylation; in vivo; interest; interstitial; mathematical model; metastatic process; migration; mortality; neoplastic cell; overexpression; physical model; podocalyxin; receptor; response; shear stress; single molecule; time use; tool; tumor