CORE D - ADMINISTRATIVE CORE - Center for the study of Reproductive Biology and

核心 D - 行政核心 - 生殖生物学和生殖生物学研究中心

• 批准号: 7684935
• 负责人: JEFFREY W. POLLARD
• 金额: $ 20.41万
• 依托单位: ALBERT EINSTEIN COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-04-01 至 2014-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7684935
• 关键词: Achievement; Basic Science; Budgets; Businesses; Clinical; Clinical Research; Collaborations; Critiques; Development; Electronic Mail; Ensure; Estrogens; Event; Faculty; Funding; Future; Goals; Grant; Group Meetings; Journals; Mammary gland; Mass Spectrum Analysis; Mission; Pilot Projects; Preparation; Proteomics; Protocols documentation; Recruitment Activity; Reporting; Reproduction; Reproductive Biology; Request for Applications; Research; Research Infrastructure; Research Personnel; Resources; Review Committee; Role; Scientific Evaluation; Series; Technology; Travel; United States National Institutes of Health; Women' s Health; Work; Writing; base; insight; meetings; member; new technology

The administrative core will provide the infrastructure for the scientific evaluation of the Center through organizing the monthly meetings for work-in-progress, collaborative project development and journal clubs. These endeavors will be enhanced by the organization of external and internal advisory boards that will allow the PI to determine scientific progress and allocation of external funds. The administrative core will also facilitate research by ensuring the necessary compliance with institutional protocols. This will be especially important because of the extensive clinical research within the Center. The core will also organize seminars that will intercalate with the extensive seminar series within Departments at AECOM. These have been very valuable in the preparation of the SCCPIR and anticipate that it will continue to be to keep the Pis of the projects at the forefront of research. The administrative core will also organize a review of pilot projects in years two to five. This will be done by requesting applications as an RFA sent out by email to all AECOM faculty. A two-page application will be requested along with NIH cv with a deadline for application. These will be assigned by Dr. Pollard to be reviewed by one member of the external and one internal advisory Board member as well as one PI on the SCCPIR grant who will score them on a NIH scale with a brief written review. The reviews will then be assessed by the Pi's on the SCCPIR (Pollard, Etgen, Santoro and Chua) and the most meritorious projects chosen for pilot funding using either SCCPIR funds or funds allocated by AECOM. The SCCPIR funded project will always be performed in collaboration with other SCCPIRs. The founding core CRB faculty of Drs Pollard, Etgen and Santoro will form an executive committee and review the budgets of the SCCPIR as presented monthly by Ms Cassidy and also the Institutional provided resources and allocate according to strategies discussed at the monthly meetings. In addition each monthly meeting of the CRB will have a business session at the beginning to review administrative matters and review strategy although not budgets. These three senior members will also attempt to identify new recruits to AECOM both in clinical and basic sciences departments whose research is appropriate for the mission of the SCCPIR and introduce them to the Center. For example the new recruit, Dr. Paraic Kenny who arrived this month and works on estrogen action in the mammary gland and the other new recruit to whom we have extended an offer if he were to come. These new members will be especially favored for CRB pilot funding. In addition, particularly talented clinical fellows will also be identified for retention at AECOM as we have in the past, with Drs. Genevieve Neal-Perry, Alex Polotsky, Lubna Pal and Satu Kuokkanen, to build the research base in clinical and translational reproductive biology. The other major scientific event that the Administrative core will organize is a once yearly meeting of the external advisory Board who will meet with all SCCPIR members and others from the CRB as well as the internal advisory board. The format of these meeting will be a one day scientific event where members will present their projects as a work-in-progress emphasizing both research achievements but also problems that need to be overcome. There will also be presentation of novel technologies (such as high-throughput mass spectroscopy and proteomic, Meso Scale Discovery technology etc) that will particularly impact research in reproduction. At the end of the day the external and internal advisory board will have an executive session with the SCCPIR Pis and co-investigators to critique the work and also provide insight into future research directions. They will also be asked to provide the PI with a written report emphasizing achievements and needs that will also be sent to Dean Spiegel. These activities and the travel of the external advisors will be cocoordinated by the administrative core

行政核心将为中心的科学评估提供基础设施， 为在制品、合作项目开发和期刊俱乐部组织月度会议。 这些努力将通过组织外部和内部咨询委员会得到加强， PI决定科学进展和外部资金的分配。行政核心还将 通过确保机构规程得到必要的遵守来促进研究。这将是特别 这是因为该中心进行了广泛的临床研究。核心还将组织研讨会 这将与AECOM各部门内的广泛研讨会系列相互交织。这些都是非常 在SCCPIR的准备中很有价值，并预计它将继续保持 处于研究前沿的项目。 行政核心还将在第二至第五年组织对试点项目的审查。会来做这项工作 要求申请作为RFA通过电子邮件发送给所有AECOM教师。一份两页的申请表将 要求沿着NIH简历，并注明申请截止日期。这些将由波拉德博士分配， 由一名外部顾问委员会成员和一名内部顾问委员会成员以及一名PI审查， SCCPIR授予谁将评分他们在美国国立卫生研究院的规模与简短的书面审查。审查将在 由Pi's对SCCPIR（Pollard，Etgen，Santoro和Chua）和最有价值的项目进行评估 选择使用SCCPIR资金或AECOM分配的资金进行试点供资。SCCPIR资助的项目 将始终与其他SCCPIR合作执行。 波拉德博士，埃特根和桑托罗的创始核心CRB教师将组成一个执行委员会，并审查 Cassidy女士每月提交的SCCPIR预算以及机构提供的资源 并根据每月会议上讨论的战略进行分配。此外，每个月的会议 审查委员会将在开始时举行一次业务会议，审查行政事务和审查战略 但不是预算。 这三位资深成员还将尝试在临床和基础方面为AECOM确定新成员 科学部门的研究是适当的SCCPIR的使命，并介绍他们的 中心例如，新招募的Paraic Kenny博士本月抵达，致力于研究雌激素的作用， 乳腺和另一个新招募的人，我们已经向他提供了一个报价，如果他来了。这些 新成员将特别受到CRB试点资金的青睐。此外，特别有才华的临床研究员 与过去一样，我们也将确定保留在AECOM，与Genevieve Neal-Perry博士，Alex Polotsky，Lubna Kazakh和Satu Kuokkanen，建立临床和转化生殖研究基地 生物学 行政核心将组织的另一项重大科学活动是每年一次的 外部咨询委员会将与SCCPIR的所有成员和CRB的其他成员以及 内部咨询委员会。这些会议的形式将是一个为期一天的科学活动，成员将 将他们的项目作为一个正在进行的工作，强调研究成果，但也存在问题， 需要克服。还将介绍新技术（如高通量大规模 光谱学和蛋白质组学，中尺度发现技术等），这将特别影响以下领域的研究： 生殖在一天结束时，外部和内部咨询委员会将举行执行会议， SCCPIR Pis和合作研究者对这项工作进行评论，并为未来的研究提供见解 方向他们还将被要求向PI提供一份强调成就的书面报告， 也会发给斯皮格尔院长将协调这些活动和外部顾问的旅行 行政核心