WASHINGTON UNIVERSITY CER MENTORED CAREER DEVELOPMENT AWARD KM1

描述（由申请人提供）：华盛顿大学医学院与美国最大、最多样化的非营利医疗系统之一BJC Healthcare有联系，其中包括两家“十大”教学医院；巴恩斯犹太医院和圣路易斯儿童医院。吴是一个优秀的环境，为研究，研究培训和临床护理。我们现正向吴大申请机构比较效能研究辅导职业发展奖（KM1） （RFA-OD-10-011），以扩充有能力进行机构比较效能研究的人手。我们将利用吴现有的基础设施，包括临床研究培训中心、公共卫生研究所和临床与转化科学研究所，来制定和实施一个新的CER职业发展计划。我们提出以下具体目标：利用研究数据、管理数据和电子健康记录开发和实施有指导的实际CER培训经验。为不同学科的CER学者和其他研究人员提供CER培训机会。2. 在华盛顿大学现有的临床研究理学硕士（MSCI）学位和新的人口健康理学硕士（MSPH）学位中开发和实施新的CER课程、课程和短期培训。在华盛顿大学临床研究培训中心设立六个新的CER学者职位，以支持博士后和初级和中期职业教师专注于CER。CER学者将参加指导的实践CER经验，教学课程和培训，以扩大和加强CER劳动力。建立一个全面的系统来评估CER职业发展计划。我们将利用实时调查和外部咨询委员会的意见来评估学者、教师、导师和培训。在未来10年内，将通过跟踪研究摘要、出版物、资助和研究中心学者和其他参与研究中心培训的人员的职业发展来衡量该项目对加强研究中心劳动力队伍的长期影响。吴有优秀的教师，导师和基础设施来支持这个新的CER职业发展计划和一个优秀的潜在学者池。在吴建立这个新的CER职业发展计划将扩大和加强有资格执行CER的研究人员的队伍，以确定在现实世界中使用的最佳治疗方法、药物和程序，以改善公众健康和降低医疗成本。

DESCRIPTION (provided by applicant): Washington University (WU) School of Medicine is linked with BJC Healthcare, one of the largest and most diverse non-profit health systems in the U.S including two "top 10" teaching hospitals; Barnes Jewish Hospital and St. Louis Children's Hospital. WU is an outstanding environment for research, research training, and clinical care. We are applying for an Institutional Comparative Effectiveness Research (CER) Mentored Career Development Award (KM1) (RFA-OD-10-011) at WU to expand the workforce capable of performing CER. We will use existing infrastructure at WU including the Center for Clinical Research Training, Institute of Public Health and Institute for Clinical and Translational Sciences to develop and implement a new CER Career Development Program. We propose the following Specific Aims: 1. Develop and implement mentored hands-on CER training experiences using research data, administrative data, and electronic health records. Provide CER training opportunities to CER scholars and other investigators from diverse disciplines. 2. Develop and implement new CER curricula, classes, and short term training in the existing Masters of Science in Clinical Investigation (MSCI) degree and the new Masters of Science in Population Health (MSPH) degree at Washington University. 3. Create six new CER scholar positions in the Clinical Research Training Center at Washington University to support postdoctoral fellows and junior and mid career faculty focused on CER. CER scholars will participate in mentored hands-on CER experiences, didactic coursework and training to expand and strengthen the CER workforce 4. Establish a comprehensive system to evaluate the CER Career Development Program. We will evaluate scholars, faculty, mentors and training using real time surveys and input from an external advisory board. The long term impact of this program to strengthen the CER workforce will be measured by tracking abstracts, publications, grants and career development of the CER scholars and others participating in the CER training over the next 10 years. WU has excellent faculty, mentors and infrastructure to support this new CER Career Development Program and an outstanding pool of potential scholars. Establishing this new CER Career Development Program at WU will expand and enhance the pool of investigators qualified to perform CER to identify the best treatments, drugs and procedures to use in real world settings to improve public health and reduce healthcare costs. PUBLIC HEALTH RELEVANCE: This grant provides protected time, salary support, and research training for investigators from diverse disciplines to obtain specialized skills in comparative effectiveness research. These well trained investigators will conduct research to determine the best treatments, tests and procedures for patients in real world settings which will improve health outcomes and reduces costs for unnecessary or ineffective treatments. Comparative effectiveness research will provide important new knowledge to inform patients, providers and payers about which treatments and procedures work best in which patients.