Identifying the epigenomic fingerprint of coronary heart disease in Chinese adults with type 2 diabetes
Identifying the epigenomic fingerprint of coronary heart disease in Chinese adults with type 2 diabetes
批准号:
nhmrc : 1113188
负责人:
Prof Assam El-Osta
金额:
$41.14万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Targeted Calls
财政年份:
2016
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2016-01-01 至 2020-12-31
中文摘要
点击翻译按钮获取中文摘要
英文摘要
Once people get diabetes, even good glucose control may be insufficient to prevent its complications. Diabetes results in molecular imprinting contributing to an increased risk of heart disease. We believe it is possible to identify this imprinted risk by a sophisticated analysis of a standard blood sample. Validating this hypothesis will lead to new biomarkers to identify individuals at increased risk of heart attacks as well as new strategies for the prevention and treatment of heart disease.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
New models of gene regulation in diabetic complications
-
批准号:nhmrc : GNT1154650
-
项目类别:Research Fellowships
-
资助金额:$64.92万
-
财政年份:2019
-
负责人:Prof Assam El-Osta
-
依托单位:
Targeting epigenetic pathways that lead to diabetic complications
-
批准号:nhmrc : GNT1142262
-
项目类别:Project Grants
-
资助金额:$98.99万
-
财政年份:2018
-
负责人:Prof Assam El-Osta
-
依托单位:
Targeting epigenetic pathways that lead to diabetic complications
-
批准号:nhmrc : 1142262
-
项目类别:Project Grants
-
资助金额:$66.93万
-
财政年份:2018
-
负责人:Prof Assam El-Osta
-
依托单位:
The Persisting Vascular Effects of Activation of the Renin-Angiotensin System
-
批准号:nhmrc : GNT1102342
-
项目类别:Project Grants
-
资助金额:$62.85万
-
财政年份:2016
-
负责人:Prof Assam El-Osta
-
依托单位:
The Persisting Vascular Effects of Activation of the Renin-Angiotensin System
-
批准号:nhmrc : 1102342
-
项目类别:Project Grants
-
资助金额:$43.12万
-
财政年份:2016
-
负责人:Prof Assam El-Osta
-
依托单位:
Epigenetic determinants of nephropathy in adults with type 1 diabetes
-
批准号:nhmrc : 1082572
-
项目类别:Project Grants
-
资助金额:$35.48万
-
财政年份:2015
-
负责人:Prof Assam El-Osta
-
依托单位:
JDRF/NHMRC Diabetes Complications Centre of Research Excellence
-
批准号:nhmrc : GNT1078609
-
项目类别:Centres of Research Excellence
-
资助金额:$250.0万
-
财政年份:2014
-
负责人:Prof Assam El-Osta
-
依托单位:
JDRF/NHMRC Diabetes Complications Centre of Research Excellence
-
批准号:nhmrc : 1078609
-
项目类别:Centres of Research Excellence
-
资助金额:$173.85万
-
财政年份:2014
-
负责人:Prof Assam El-Osta
-
依托单位:
Development and Epilepsy - Strategies for Innovative Research to improve diagnosis, prevention and treatment in children with difficult to treat Epilepsy
-
批准号:nhmrc : 1075563
-
项目类别:Targeted Calls
-
资助金额:$30.41万
-
财政年份:2014
-
负责人:Prof Assam El-Osta
-
依托单位:
Role of Set7 in diabetes related end-organ injury
-
批准号:nhmrc : 1027341
-
项目类别:Project Grants
-
资助金额:$60.27万
-
财政年份:2012
-
负责人:Prof Assam El-Osta
-
依托单位:
Uncoupled Research Fellowship
-
批准号:nhmrc : 526681
-
项目类别:NHMRC Research Fellowships
-
资助金额:$47.37万
-
财政年份:2009
-
负责人:Prof Assam El-Osta
-
依托单位:
Role of chromatin remodelling in diabetic renal and vascular complications: in vivo studies
-
批准号:nhmrc : 526685
-
项目类别:NHMRC Project Grants
-
资助金额:$31.65万
-
财政年份:2009
-
负责人:Prof Assam El-Osta
-
依托单位:
Functional Significance of MeCP2 Target Genes in the Pathogenesis of Rett Syndrome.
-
批准号:nhmrc : 457238
-
项目类别:NHMRC Project Grants
-
资助金额:$31.79万
-
财政年份:2007
-
负责人:Prof Assam El-Osta
-
依托单位:
The generlaity of the SWI/SNF regulatory complex in mental health and cardiovascular disease
-
批准号:nhmrc : 367647
-
项目类别:Career Development Fellowships
-
资助金额:$18.14万
-
财政年份:2006
-
负责人:Prof Assam El-Osta
-
依托单位:
Role of epigenetic mechanisms in diabetic vascular complications
-
批准号:nhmrc : 367621
-
项目类别:NHMRC Project Grants
-
资助金额:$29.24万
-
财政年份:2006
-
负责人:Prof Assam El-Osta
-
依托单位:
Characterisation of the anti-apoptotic function of P-glycoprotein and transcriptional regulation of the MDR1 gene.
-
批准号:nhmrc : 350308
-
项目类别:NHMRC Project Grants
-
资助金额:$31.31万
-
财政年份:2005
-
负责人:Prof Assam El-Osta
-
依托单位:
A new paradigm for SWI/SNF chromatin function; the ATPase dependent remodeler is a component of the MeCP2 complex
-
批准号:nhmrc : 268905
-
项目类别:NHMRC Project Grants
-
资助金额:$16.95万
-
财政年份:2004
-
负责人:Prof Assam El-Osta
-
依托单位:
Characterisation of the anti-apoptotic function of P-glycoprotein and transcriptional regulation of the MDR1 gene
-
批准号:nhmrc : 208930
-
项目类别:NHMRC Project Grants
-
资助金额:$21.61万
-
财政年份:2002
-
负责人:Prof Assam El-Osta
-
依托单位:
海外基金