TRAINING PROGRAM IN THE BIOLOGY OF DISEASE VECTORS

描述(申请人提供)：认识到遏制媒介传播疾病传播的必要性，加州大学戴维斯分校最近批准了媒介传播疾病生物学的指定重点，其目标是培训研究生和研究生，了解媒介传播的人类和动物疾病的病毒、细菌和寄生虫病原体及其节肢动物媒介的生物学。需要资金来加强这一新的培训方案，在为期5年的资助期内，每年为2名博士前和2名博士后学员提供支助。此外，加州大学戴维斯分校还提供了院校配套资金，以支持另外两名博士生。这项多学科培训计划将由格雷戈里·兰扎罗博士指导，总部设在媒介传播疾病中心，将有来自兽医和医学院以及农业和环境科学学院的高素质、资金充足的培训教师参加。博士前实习生将从昆虫学系以及生物化学和分子生物学、比较病理学、流行病学、免疫学和微生物学等六个附属博士项目中招募。受训者将由咨询和招生委员会根据学术成就和对媒介传播疾病生物学表现出的兴趣进行挑选，并从代表性不足的种族和族裔群体、残疾个人和弱势背景个人中进行特别招聘。培训课程将提供微生物学、免疫学、流行病学、遗传学、病原体和节肢动物媒介的种群基因组学、媒介生态学和控制、疾病病理学和诊断等教学课程。此外，受训人员将参加关于负责任的研究行为的课程，以及由研究办公室和研究生研究办公室提供的关于研究道德的一系列讲座讨论和嘉宾演讲研讨会。受训者将被要求参加与培训计划相关的主题的研究研讨会和讨论小组，并在年度研究静修会上展示他们的研究。每个学员的学业进步将由咨询和招生委员会每年进行审查。 相关性：医学研究所(LOM)最近的报告，包括2003年、2006年和2008年，都强调美国缺乏媒介传播疾病的专业知识。然而，媒介传播疾病仍然是国内和国际上最重要的人类和兽医健康问题之一。这项修订后的T32培训助学金申请侧重于对博士后和博士后学者进行人类和动物疾病节肢动物媒介生物学方面的培训。

DESCRIPTION (provided by applicant): Recognizing the need to curb the spread of vectorborne diseases, the University of California at Davis has recently approved a Designated Emphasis in the Biology of Vectorborne Diseases, the goal of which is to train graduate and postgraduate fellows in the biology of vectorborne viral, bacterial, and parasitic agents of human and animal diseases and their arthropod vectors. Funds are requested to enhance this new training program by providing support for two pre-doctoral and 2 post-doctoral trainees per year for a 5-year funding period. In addition, UC Davis has provided institutional matching funds to support two additional Ph.D. students. The multidisciplinary training program, which will be directed by Dr. Gregory Lanzaro, will be based in the Center for Vectorborne Diseases, and will involve a highly qualified, well-funded training faculty from the Schools of Veterinary Medicine and Medicine and the College of Agricultural and Environmental Sciences. The pre-doctoral trainees will be recruited from six affiliated Ph.D. programs, namely the Department of Entomology, and the Graduate Groups in Biochemistry and Molecular Biology, Comparative Pathology, Epidemiology, Immunology, and Microbiology. Trainees will be selected by an Advisory and Admissions Committee based upon academic excellence and demonstrated interest in the biology of vectorborne diseases, with special recruitment effort from underrepresented racial and ethnic groups, individuals with disabilities, and individuals from disadvantaged backgrounds. Didactic courses in microbiology, immunology, epidemiology, genetics, population genomics of pathogens and arthropod vectors, vector ecology and control, disease pathology and diagnosis will be offered in the curriculum for trainees. In addition, trainees will attend courses on responsible conduct of research as well as a series of lecture-discussion and guest-speaker seminars on research ethics offered through the Office of Research and Office of Graduate Studies. Trainees will be required to attend research seminars and discussion groups on topics relevant to the training program and present their research at an annual research retreat. Each trainee's academic progress will be reviewed annually by an Advisory and Admissions Committee. RELEVANCE: Recent Institute of Medicine (lOM) reports, including 2003, 2006, and 2008, all emphasize a deficiency of expertise in vectorborne diseases in U.S.A. Yet, vectorborne diseases remain among the most important human and veterinary health problems, both nationally and internationally. This revised T32 Training Grant application focuses on training pre-doctoral and post-doctoral scholars in the biology of arthropod vectors of human and animal diseases.