Recruitment of a Bone and Cancer Early Stage Investigator

招募骨与癌症早期研究员

• 批准号: 7859361
• 负责人: D Rick Sumner
• 金额: $ 38.28万
• 依托单位: RUSH UNIVERSITY MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-29 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7859361
• 关键词: Academic Medical Centers; Anatomy; Area; Basic Science; Cancer Biology; Cancer Grant Supplements (P30); Cancer Research Project; Cellular biology; Clinical; Commit; Connective Tissue; Development; Eligibility Determination; Faculty; Funding; Goals; Grant; Gynecologic Oncology; Hematologic Neoplasms; Interview; Laboratories; Leadership; Learning; Ligaments; Malignant Bone Neoplasm; Malignant Neoplasms; Malignant neoplasm of lung; Medical center; Metastatic Neoplasm to the Bone; Mission; Neoplasm Metastasis; Orthopedic Surgery procedures; Orthopedics; Patients; Phase; Positioning Attribute; Recruitment Activity; Research; Research Activity; Research Personnel; Resistance; Staging; Tendon structure; United States National Institutes of Health; Work; anticancer research; articular cartilage; base; bone; cancer stem cell; career; design; experience; improved; malignant breast neoplasm; meetings; member; oncology; programs; skeletal

DESCRIPTION (Provided by the applicant): The goal of this project is to continue the development of a Core Center in Bone and Cancer at Rush University Medical Center by facilitating the recruitment of a new early stage investigator to a tenure-track faculty position. The Medical Center has a large group of basic and translational researchers focusing on connective tissues, particularly bone, articular cartilage and tendons and ligaments. Two important strategic focus areas for the Medical Center include orthopedics and cancer, as evidenced by a number of building projects, new recruits and the nearly completed recruitment of a cancer director. As a cooperative venture between the Department of Anatomy & Cell Biology and the Department of Orthopedic Surgery, we have recently recruited a senior, NIH funded, faculty member with expertise in cancer biology into our newly established bone and cancer program. Through this grant mechanism, we now propose to expand the bone and cancer program by recruiting a laboratory-based early stage investigator who is committed to a career working with clinicians in the design and implementation of translational cancer research. We have already completed the initial search phase and have interviewed three outstanding candidates. Among these candidates, we have prioritized our ranking based on the "fit" between the candidate's research area and expressed desire to have a strong translational component and our clinical and basic science research strengths. The major mission of the Bone and Cancer is to advance patient treatment through improved understanding of cancer survival and metastasis mechanisms. A great deal is now being learned about the potential importance of cancer stem cells in resistance to treatment and the bone microenvironment in bone metastases. The development of a Bone and Cancer Core Center represents an ideal way to bolster cancer research activity at Rush since the great strengths in skeletal research and clinical orthopedic oncology can be leveraged to provide administrative and scientific support for the proposed activities.

描述（由申请人提供）：该项目的目标是继续在拉什大学医学中心的骨和癌症的核心中心的发展，促进新的早期阶段的研究人员招聘到终身教职。医学中心拥有大量基础和转化研究人员，专注于结缔组织，特别是骨骼，关节软骨和肌腱和韧带。医疗中心的两个重要战略重点领域包括骨科和癌症，这一点可以从一些建筑项目、新招聘人员和即将完成的癌症主任招聘工作中得到证明。作为一个合作企业， 解剖学与细胞生物学和骨科手术系，我们最近招募了一位资深的，NIH资助的，在癌症生物学方面具有专业知识的教员到我们新成立的骨骼和癌症计划。通过这一赠款机制，我们现在建议通过招募一名实验室早期研究人员来扩大骨与癌症项目，该研究人员致力于与临床医生一起设计和实施转化癌症研究。我们已经完成了初步的搜索阶段，并面试了三名优秀的候选人。在这些候选人中，我们根据候选人的研究领域之间的“适合度”优先排序，并表示希望拥有强大的翻译组件和我们的临床和基础科学研究优势。骨与癌症的主要使命是通过提高对癌症生存和转移机制的理解来推进患者治疗。目前，人们对癌症干细胞在抵抗治疗和骨转移中的骨微环境的潜在重要性有了大量的了解。骨和癌症核心中心的发展代表了一个理想的方式，以支持癌症研究活动在拉什，因为在骨骼研究和临床骨科肿瘤学的巨大优势，可以利用提供行政和科学支持拟议的活动。