ASSESSMENT OF FITNESS IN ASMATIC CHILDREN

无乳房儿童的健康评估

• 批准号: 7951059
• 负责人: CHRISTINA DANELL SCHWINDT
• 金额: $ 2.09万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-12-01 至 2009-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7951059
• 关键词: Age; Arts; Asthma; Body Composition; Bronchodilator Agents; Child; Clinical Research; Computer Retrieval of Information on Scientific Projects Database; DEXA; Exercise; Funding; Grant; Guidelines; Institution; Link; Literature; National Heart, Lung, and Blood Institute; Obesity; Physical activity; Prevalence; Pulmonary function tests; Questionnaires; Research; Research Personnel; Resources; Scanning; Severities; Source; Surveys; Symptoms; United States National Institutes of Health; base; fitness; lifestyle factors; response

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Purpose: The purpose of this study is to assess the level of fitness in asthmatic children and correlate this assessment with asthma severity and response to bronchodilator. Hypothesis: We hypothesize that decreased fitness levels in asthmatic children correlates with increasing asthma severity. SPECIFIC AIMS: Specific Aim 1: To determine the level of fitness in asthmatic children using a comprehensive and state-of-the-art approach through 1) an exercise challenge and 2) body composition, as assessed through a DEXA scan. Specific Aim 2: To determine subject asthma severity, based on NHLBI guidelines, as assessed through 1) pulmonary function testing 2) response to bronchodilator and 3) a questionnaire of asthma symptoms. Specific Aim 3: To assess the level of habitual physical activity in asthmatic children through validated, age appropriate surveys. Background: There is a growing body of literature that implicates lifestyle factors, in particular physical inactivity, as a contributor to the increase in asthma prevalence and severity. Indeed, numerous studies link body composition (obesity) to asthma. However, the level of fitness in asthmatics has been poorly assessed, particularly as correlated to asthma severity. This study proposes to study the fitness level of asthmatic children and correlate asthma severity levels to degree of fitness.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 目的：本研究的目的是评估哮喘儿童的健康水平，并将此评估与哮喘严重程度和对支气管扩张剂的反应相关联。 假设：我们假设哮喘儿童健康水平下降与哮喘严重程度增加相关。 具体目标： 具体目标1：通过1）运动挑战和2）身体成分（通过DEXA扫描评估），使用综合和最先进的方法确定哮喘儿童的健康水平。 具体目标二：根据NHLBI指南，通过1）肺功能检查2）对支气管扩张剂的反应和3）哮喘症状问卷评估，确定受试者哮喘严重程度。 具体目标3： 通过有效的、适合年龄的调查评估哮喘儿童的习惯性体力活动水平。 背景资料：越来越多的文献表明，生活方式因素，特别是身体活动不足，是哮喘患病率和严重程度增加的一个因素。 事实上，许多研究将身体成分（肥胖）与哮喘联系起来。 然而，哮喘患者的健康水平评估得很差，特别是与哮喘严重程度相关的健康水平。 本研究拟探讨气喘儿童之体能水平，并探讨气喘严重程度与体能程度之相关性。