A PILOT OPEN-LABELED TRIAL OF SAM-E FOR RECURRENT ABDOMINAL PAIN IN CHILDREN

SAM-E 治疗儿童复发性腹痛的开放标签试点试验

• 批准号: 7950972
• 负责人: Jeannie S Huang
• 金额: $ 0.45万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-12-01 至 2009-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7950972
• 关键词: Abdominal Pain; Child; Clinical Research; Computer Retrieval of Information on Scientific Projects Database; Funding; Grant; Institution; Pain; Recurrence; Research; Research Personnel; Resources; Source; Symptoms; United States National Institutes of Health; depressive symptoms; disability; health related quality of life; open label; pilot trial

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We will evaluate SAM-e as a treatment for recurrent abdominal pain (RAP) in children in an open labeled pilot trial. Our specific aims will be: 1. To determine whether SAM-e reduces pain intensity, non-pain symptoms, pain disability, and depressive symptoms in children with recurrent abdominal pain. 2. To determine whether SAM-e increases the health-related quality of life in children with recurrent abdominal pain.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 我们将在一项开放标签试点试验中评估 SAM-e 作为儿童复发性腹痛 (RAP) 的治疗方法。我们的具体目标是： 1. 确定 SAM-e 是否可以减轻复发性腹痛儿童的疼痛强度、非疼痛症状、疼痛失能和抑郁症状。 2. 确定 SAM-e 是否可以提高患有复发性腹痛的儿童的健康相关生活质量。