PROTEIN PHOSPHORYLATION IN YEAST VACUOLE FUSION

酵母液泡融合中的蛋白质磷酸化

• 批准号: 7957800
• 负责人: Alexey Jarrell Merz
• 金额: $ 0.33万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-01 至 2010-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7957800
• 关键词: Biology; Chimeric Proteins; Complex; Computer Retrieval of Information on Scientific Projects Database; Docking; Funding; Fungal Genome; Goals; Grant; Institution; Membrane Fusion; Phosphorylation; Proteins; Research; Research Personnel; Resources; Role; SNAP receptor; Source; United States National Institutes of Health; Vacuole; Yeasts; interest; rab GTP-Binding Proteins

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We are interested in the roles of several proteins involved in yeast vacuole membrane fusion, including a Rab GTPase (Ypt7p), its effector complex (HOPS), and vacuolar SNARE proteins (Vam3p, Vam7p, Vti1p, Nyv1p). Our goal is to generate a phosphorylation profile of known docking and fusion proteins, and to identify new fusion machinery.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 我们感兴趣的几个蛋白质参与酵母液泡膜融合，包括一个Rab GT3（Ypt 7 p），其效应复合物（HOPS），和液泡陷阱蛋白（Vam 3 p，Vam 7 p，Vti 1 p，Nyv 1 p）的作用。我们的目标是产生已知的对接和融合蛋白的磷酸化概况，并确定新的融合机制。