PROTEIN INTERACTIONS WITH VACUOLE TARGETING MACHINERY

蛋白质与液泡靶向机制的相互作用

• 批准号: 7957852
• 负责人: Alexey Jarrell Merz
• 金额: $ 0.74万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-01 至 2010-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7957852
• 关键词: Affinity Chromatography; Biology; Computer Retrieval of Information on Scientific Projects Database; Funding; Fungal Genome; Goals; Grant; Institution; Proteins; Research; Research Personnel; Resources; Source; United States National Institutes of Health; Vacuole; novel; protein transport

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We have developed affinity chromatography approaches to identify proteins that interact specifically with proteins involved in vesicular protein trafficking machinery. These approaches result in the purification and enrichment of both previously studied proteins and proteins not yet identified. Our goal is to identify and characterize these novel factors.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 我们开发了亲和层析方法来识别与参与囊泡蛋白运输机制的蛋白质特异性相互作用的蛋白质。这些方法导致了先前研究的蛋白质和尚未鉴定的蛋白质的纯化和富集。我们的目标是识别和表征这些新因素。