DNA DAMAGE RECOGNITION AND REPAIR DURING CELL DIVISION

细胞分裂过程中 DNA 损伤的识别和修复

• 批准号: 7954837
• 负责人: Michael W. Berns
• 金额: $ 0.3万
• 依托单位: UNIVERSITY OF CALIFORNIA-IRVINE
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-04-01 至 2010-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7954837
• 关键词: Affect; Biotechnology; Cell division; Cells; Chromosome Segregation; Computer Retrieval of Information on Scientific Projects Database; DNA Damage; DNA Double Strand Break; Funding; Generations; Grant; Institution; Lasers; Mitosis; Research; Research Personnel; Resources; Source; United States National Institutes of Health; Work; daughter cell; repaired; response

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The aim is to characterize the cellular response to DNA double strand break damage during mitosis in mamalian cells. The scope of this work will include affects on spindle checkpoint, proper segregation of chromosomes and generation of daughter cells.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 目的是表征哺乳动物细胞有丝分裂过程中DNA双链断裂损伤的细胞反应。 这项工作的范围将包括对纺锤体检查点的影响，染色体的正确分离和子细胞的产生。