STUDIES ON ENZYMES INVOLVED IN THE GLOBAL CYCLING OF HYDROGEN, NITROGEN AND CARB

参与氢、氮和碳水化合物全球循环的酶的研究

基本信息

  • 批准号:
    7954345
  • 负责人:
  • 金额:
    $ 0.75万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2009
  • 资助国家:
    美国
  • 起止时间:
    2009-03-01 至 2010-02-28
  • 项目状态:
    已结题

项目摘要

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The following program proposal narrative describes individual experiments for several projects that involve the use of synchrotron radiation for structure determination using x-ray diffraction methods to address problems concerning the mechanism of enzyme catalyzed reactions. Toward these ends, we are determining the structure of novel enzymes and utilizing information obtained by previous biochemical and biophysical studies as a basis for capturing and determining the structure of enzymes in defined states that mimic intermediates along the pathway of catalysis. The overall goal of these studies is to utilize the structures of defined states of certain enzymes to contribute to the overall understanding of enzyme mechanism and therefore there is significant value in conducting these studies at high resolution. We are currently pursuing these studies for enzymes involved in hydrogen production, nitrogen reduction, phosphate ester hydrolysis, and bioconversion of alkenes and ketones.
这个子项目是众多研究子项目之一

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

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JOHN W PETERS其他文献

JOHN W PETERS的其他文献

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{{ truncateString('JOHN W PETERS', 18)}}的其他基金

Defining the mechanistic determinants of catalytic bias in cofactor-based enzymatic oxidation-reduction reactions
定义基于辅因子的酶促氧化还原反应中催化偏差的机械决定因素
  • 批准号:
    10874184
  • 财政年份:
    2020
  • 资助金额:
    $ 0.75万
  • 项目类别:
Defining the mechanistic determinants of catalytic bias in cofactor-based enzymatic oxidation-reduction reactions
定义基于辅因子的酶促氧化还原反应中催化偏差的机械决定因素
  • 批准号:
    10034848
  • 财政年份:
    2020
  • 资助金额:
    $ 0.75万
  • 项目类别:
Defining the mechanistic determinants of catalytic bias in cofactor-based enzymatic oxidation-reduction reactions
定义基于辅因子的酶促氧化还原反应中催化偏差的机械决定因素
  • 批准号:
    10437871
  • 财政年份:
    2020
  • 资助金额:
    $ 0.75万
  • 项目类别:
Defining the mechanistic determinants of catalytic bias in cofactor-based enzymatic oxidation-reduction reactions
定义基于辅因子的酶促氧化还原反应中催化偏差的机械决定因素
  • 批准号:
    10259728
  • 财政年份:
    2020
  • 资助金额:
    $ 0.75万
  • 项目类别:
Defining the mechanistic determinants of catalytic bias in cofactor-based enzymatic oxidation-reduction reactions
定义基于辅因子的酶促氧化还原反应中催化偏差的机械决定因素
  • 批准号:
    10645050
  • 财政年份:
    2020
  • 资助金额:
    $ 0.75万
  • 项目类别:
STUDIES ON ENZYMES INVOLVED IN THE GLOBAL CYCLING OF HYDROGEN, NITROGEN AND CARB
参与氢、氮和碳水化合物全球循环的酶的研究
  • 批准号:
    8362120
  • 财政年份:
    2011
  • 资助金额:
    $ 0.75万
  • 项目类别:
STUDIES ON ENZYMES INVOLVED IN THE GLOBAL CYCLING OF HYDROGEN, NITROGEN AND CARB
参与氢、氮和碳水化合物全球循环的酶的研究
  • 批准号:
    8170030
  • 财政年份:
    2010
  • 资助金额:
    $ 0.75万
  • 项目类别:
PROBING NITROGENASE FE PROTEIN NUCLEOTIDE DEPENDENT CONFORMATIONAL CHANGES USING
使用 探测固氮酶 FE 蛋白质核苷酸依赖的构象变化
  • 批准号:
    8170039
  • 财政年份:
    2010
  • 资助金额:
    $ 0.75万
  • 项目类别:
PROBING NITROGENASE FE PROTEIN NUCLEOTIDE DEPENDENT CONFORMATIONAL CHANGES USING
使用 探测固氮酶 FE 蛋白质核苷酸依赖的构象变化
  • 批准号:
    7954363
  • 财政年份:
    2009
  • 资助金额:
    $ 0.75万
  • 项目类别:
STUDIES ON ENZYMES INVOLVED IN THE GLOBAL CYCLING OF HYDROGEN, NITROGEN AND CARB
参与氢、氮和碳水化合物全球循环的酶的研究
  • 批准号:
    7721997
  • 财政年份:
    2008
  • 资助金额:
    $ 0.75万
  • 项目类别:

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用于烯烃 MHAT 加氢官能化的双功能催化剂
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    2024
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