BIOMECHANICS CORE
BIOMECHANICS CORE
批准号:
7802705
负责人:
JAMES Anthony ASHTON-MILLER
金额:
$12.84万
依托单位国家:
美国
项目类别:
财政年份:
2009
资助国家:
美国
项目状态:
已结题
起止时间:
2009-09-30 至 2014-08-31
关键词:
AffectAgeAgingAmericanAreaBiomechanicsCenters for Disease Control and Prevention (U.S.)CharacteristicsCollaborationsComputer SimulationDeteriorationDiagnosisDiagnostic testsDisciplineElderlyEquilibriumExerciseFacultyFemaleFosteringFunctional disorderFundingFutureGaitGoalsImpairmentIndividualInjuryLifeMaintenanceMeasurementMentorshipMethodsMissionMuscle ContractionMusculoskeletal EquilibriumNeurologicPatientsPelvic floor structurePhenotypePhysiologicalPilot ProjectsPreventionPrevention ProtocolsProcessProtocols documentationPtosisPublished CommentResearchResearch PersonnelResearch TrainingRoleServicesSurfaceSyndromeTechnical ExpertiseTechnology TransferTestingTrainingUrethraUrinary Incontinenceagedbench to bedsidecareer developmentdata acquisitiondesigndisabilityeffective therapyexperiencefallsinjury preventioninsightinterestmotor controlprogramsranpirnaseresponsesphincter ani muscle structure
中文摘要
点击翻译按钮获取中文摘要
英文摘要
Whatever the underlying physiologic or neurologic mechanisms, questions about loss of mobility, deterioration of motor
control, responses to impending falls, maintenance of balance and postural control, changes in muscle
contraction characteristics and maintenance of continence are ultimately biomechanical questions (Ashton-Miller & Alexander, 2003). The facilities of the Biomechanics Core will enable examination of such questions quantitatively, from the viewpoint of
biomechanics and other physiological measurements. In particular the Biomechanics Core will contribute to
the mission of the UM Pepper Center by fostering research Into the mechanisms by which certain
predictor and modifying variables earlier in life may affect the expression of aged phenotypes.
Applications of Biomechanics Research: There is ample justification for funding research and research
training that help examine the role of biomechanical and other physiological mechanisms that contribute to
the aged phenotypes as well as to physical impairments, syndromes and disability in elderfy people. The
insights such research will provide apply to (1) designing diagnostic tests that can quantify precisely
physical impairment in elderiy people, (2) designing more effective therapy programs for elderiy people who
are already impaired, (3) designing protocols, such as exercise protocols, for prevention of physical
impairments in elderiy people. Areas of particular interest include aging, gait on regular and irregular surfaces,
mobility, fall-related injuries, as well as female pelvic floor function, urinary incontinence and prolapse, and (4) in
transferring technology from bench to bedside. The latter goals are consistent with the CDC Injury Prevention
Agenda 2009-2018 (National Center for Injury Prevention and Control, 2009).
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Development of 21st Century Concepts and Tools for Quantifying Urethral Failure Mechanisms that Cause Urinary Incontinence
-
批准号:10217124
-
项目类别:
-
资助金额:$112.79万
-
财政年份:2019
-
负责人:JAMES Anthony ASHTON-MILLER
-
依托单位:
Development of 21st Century Concepts and Tools for Quantifying Urethral Failure Mechanisms that Cause Urinary Incontinence
-
批准号:10019378
-
项目类别:
-
资助金额:$116.33万
-
财政年份:2019
-
负责人:JAMES Anthony ASHTON-MILLER
-
依托单位:
Development of 21st Century Concepts and Tools for Quantifying Urethral Failure Mechanisms that Cause Urinary Incontinence
-
批准号:10449216
-
项目类别:
-
资助金额:$113.51万
-
财政年份:2019
-
负责人:JAMES Anthony ASHTON-MILLER
-
依托单位:
Development of 21st Century Concepts and Tools for Quantifying Urethral Failure Mechanisms that Cause Urinary Incontinence
-
批准号:9815669
-
项目类别:
-
资助金额:$122.52万
-
财政年份:2019
-
负责人:JAMES Anthony ASHTON-MILLER
-
依托单位:
BIOMECHANICS OF SIMULATED VAGINAL BIRTH
-
批准号:7715230
-
项目类别:
-
资助金额:$22.45万
-
财政年份:2008
-
负责人:JAMES Anthony ASHTON-MILLER
-
依托单位:
MEASUREMENT AND IMAGING CORE
-
批准号:7699807
-
项目类别:
-
资助金额:$22.45万
-
财政年份:2008
-
负责人:JAMES Anthony ASHTON-MILLER
-
依托单位:
New Perspectives on ACL Injury
-
批准号:9521352
-
项目类别:
-
资助金额:$31.49万
-
财政年份:2007
-
负责人:JAMES Anthony ASHTON-MILLER
-
依托单位:
New Perspectives on ACL Injury
-
批准号:9889886
-
项目类别:
-
资助金额:$29.68万
-
财政年份:2007
-
负责人:JAMES Anthony ASHTON-MILLER
-
依托单位:
Biomechanics Core
-
批准号:10448479
-
项目类别:
-
资助金额:$14.89万
-
财政年份:2004
-
负责人:JAMES Anthony ASHTON-MILLER
-
依托单位:
Biomechanics Core
-
批准号:10221527
-
项目类别:
-
资助金额:$18.37万
-
财政年份:2004
-
负责人:JAMES Anthony ASHTON-MILLER
-
依托单位:
Biomechanics Core
-
批准号:8877054
-
项目类别:
-
资助金额:$7.68万
-
财政年份:2004
-
负责人:JAMES Anthony ASHTON-MILLER
-
依托单位:
CORE--BIOMECHANICS
-
批准号:6847279
-
项目类别:
-
资助金额:$16.9万
-
财政年份:2004
-
负责人:JAMES Anthony ASHTON-MILLER
-
依托单位:
Biomechanics Core
-
批准号:10668408
-
项目类别:
-
资助金额:$15.52万
-
财政年份:2004
-
负责人:JAMES Anthony ASHTON-MILLER
-
依托单位:
CORE--BIOMECHANICS
-
批准号:6651212
-
项目类别:
-
资助金额:$19.62万
-
财政年份:2002
-
负责人:JAMES Anthony ASHTON-MILLER
-
依托单位:
CORE--BIOMECHANICS
-
批准号:6482376
-
项目类别:
-
资助金额:$19.62万
-
财政年份:2001
-
负责人:JAMES Anthony ASHTON-MILLER
-
依托单位:
CORE--BIOMECHANICS
-
批准号:6352540
-
项目类别:
-
资助金额:$19.62万
-
财政年份:2000
-
负责人:JAMES Anthony ASHTON-MILLER
-
依托单位:
CORE--BIOMECHANICS
-
批准号:6348880
-
项目类别:
-
资助金额:$14.27万
-
财政年份:2000
-
负责人:JAMES Anthony ASHTON-MILLER
-
依托单位:
PHYSICAL & PSYCHOLOGICAL FACTORS IN MOBILITY
-
批准号:6299332
-
项目类别:
-
资助金额:$17.32万
-
财政年份:2000
-
负责人:JAMES Anthony ASHTON-MILLER
-
依托单位:
SPECIFIC EDUCATION, EXERCISE, AND STRESS INCONTINENCE
-
批准号:6098224
-
项目类别:
-
资助金额:$1.0万
-
财政年份:1999
-
负责人:JAMES Anthony ASHTON-MILLER
-
依托单位:
PHYSICAL & PSYCHOLOGICAL FACTORS IN MOBILITY
-
批准号:6098422
-
项目类别:
-
资助金额:$17.32万
-
财政年份:1999
-
负责人:JAMES Anthony ASHTON-MILLER
-
依托单位:
国内基金
海外基金
登录
查看更多内容
补阳还五汤通过AGE-RAGE通路调控脓毒症免疫失衡的机制与转化研究
-
批准号:JCZRLH202601523
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2026
-
负责人:
-
依托单位:
靶向递送一氧化碳调控AGE-RAGE级联反应促进糖尿病创面愈合研究
-
批准号:JCZRQN202500010
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2025
-
负责人:
-
依托单位:
对香豆酸抑制AGE-RAGE-Ang-1通路改善海马血管生成障碍发挥抗阿尔兹海默病作用
-
批准号:2025JJ70209
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2025
-
负责人:雷芬芳
-
依托单位:
AGE-RAGE通路调控慢性胰腺炎纤维化进程的作用及分子机制
-
批准号:--
-
项目类别:面上项目
-
资助金额:--
-
批准年份:2024
-
负责人:万荣
-
依托单位:
甜茶抑制AGE-RAGE通路增强突触可塑性改善小鼠抑郁样行为
-
批准号:2023JJ50274
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2023
-
负责人:贺志明
-
依托单位:
蒙药额尔敦-乌日勒基础方调控AGE-RAGE信号通路改善术后认知功能障碍研究
-
批准号:--
-
项目类别:地区科学基金项目
-
资助金额:33万元
-
批准年份:2022
-
负责人:都义日
-
依托单位:
补肾健脾祛瘀方调控AGE/RAGE信号通路在再生障碍性贫血骨髓间充质干细胞功能受损的作用与机制研究
-
批准号:--
-
项目类别:面上项目
-
资助金额:52万元
-
批准年份:2022
-
负责人:叶宝东
-
依托单位:
LncRNA GAS5在2型糖尿病动脉粥样硬化中对AGE-RAGE 信号通路上相关基因的调控作用及机制研究
-
批准号:
-
项目类别:省市级项目
-
资助金额:10.0万元
-
批准年份:2022
-
负责人:于海兵
-
依托单位:
围绕GLP1-Arginine-AGE/RAGE轴构建探针组学方法探索大柴胡汤异病同治的效应机制
-
批准号:81973577
-
项目类别:面上项目
-
资助金额:55.0万元
-
批准年份:2019
-
负责人:辛贵忠
-
依托单位:
AGE/RAGE通路microRNA编码基因多态性与2型糖尿病并发冠心病的关联研究
-
批准号:81602908
-
项目类别:青年科学基金项目
-
资助金额:18.0万元
-
批准年份:2016
-
负责人:刘括
-
依托单位: