BIOMECHANICS CORE

生物力学核心

• 批准号: 7802705
• 负责人: JAMES Anthony ASHTON-MILLER
• 金额: $ 12.84万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-30 至 2014-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7802705
• 关键词: Affect; Age; Aging; American; Area; Biomechanics; Centers for Disease Control and Prevention (U.S.); Characteristics; Collaborations; Computer Simulation; Deterioration; Diagnosis; Diagnostic tests; Discipline; Elderly; Equilibrium; Exercise; Faculty; Female; Fostering; Functional disorder; Funding; Future; Gait; Goals; Impairment; Individual; Injury; Life; Maintenance; Measurement; Mentorship; Methods; Mission; Muscle Contraction; Musculoskeletal Equilibrium; Neurologic; Patients; Pelvic floor structure; Phenotype; Physiological; Pilot Projects; Prevention; Prevention Protocols; Process; Protocols documentation; Ptosis; Published Comment; Research; Research Personnel; Research Training; Role; Services; Surface; Syndrome; Technical Expertise; Technology Transfer; Testing; Training; Urethra; Urinary Incontinence; aged; bench to bedside; career development; data acquisition; design; disability; effective therapy; experience; falls; injury prevention; insight; interest; motor control; programs; ranpirnase; response; sphincter ani muscle structure

Whatever the underlying physiologic or neurologic mechanisms, questions about loss of mobility, deterioration of motor control, responses to impending falls, maintenance of balance and postural control, changes in muscle contraction characteristics and maintenance of continence are ultimately biomechanical questions (Ashton-Miller & Alexander, 2003). The facilities of the Biomechanics Core will enable examination of such questions quantitatively, from the viewpoint of biomechanics and other physiological measurements. In particular the Biomechanics Core will contribute to the mission of the UM Pepper Center by fostering research Into the mechanisms by which certain predictor and modifying variables earlier in life may affect the expression of aged phenotypes. Applications of Biomechanics Research: There is ample justification for funding research and research training that help examine the role of biomechanical and other physiological mechanisms that contribute to the aged phenotypes as well as to physical impairments, syndromes and disability in elderfy people. The insights such research will provide apply to (1) designing diagnostic tests that can quantify precisely physical impairment in elderiy people, (2) designing more effective therapy programs for elderiy people who are already impaired, (3) designing protocols, such as exercise protocols, for prevention of physical impairments in elderiy people. Areas of particular interest include aging, gait on regular and irregular surfaces, mobility, fall-related injuries, as well as female pelvic floor function, urinary incontinence and prolapse, and (4) in transferring technology from bench to bedside. The latter goals are consistent with the CDC Injury Prevention Agenda 2009-2018 (National Center for Injury Prevention and Control, 2009).

无论潜在的生理或神经机制如何，关于活动能力丧失、运动功能退化的问题 控制，对即将发生的福尔斯的反应，平衡和姿势控制的维持，肌肉的变化 收缩特性和维持血管的最终是生物力学问题（Ashton-Miller &亚历山大，2003）。生物力学核心的设施将能够从以下角度定量地检查这些问题： 生物力学和其他生理测量。特别是生物力学核心将有助于 UM胡椒中心的使命，通过促进对某些 生命早期的预测变量和修正变量可能会影响老年表型的表达。 生物力学研究的应用：有充分的理由资助研究和研究 训练有助于检查生物力学和其他生理机制的作用， 老年表型以及老年人的身体损伤、综合征和残疾。的 这些研究将提供的见解适用于（1）设计可以精确量化的诊断测试 老年人的身体缺陷，（2）为老年人设计更有效的治疗方案， 已经受损，（3）设计协议，如锻炼协议，以防止身体 老年人的残疾。特别感兴趣的领域包括老化，在规则和不规则表面上的步态， 活动性、跌倒相关损伤以及女性盆底功能、尿失禁和脱垂，以及（4） 将技术从实验室转移到临床后者的目标与CDC伤害预防一致 2009-2018年议程（国家伤害预防和控制中心，2009年）。