The BLSA Home Visit Program

BLSA 家访计划

• 批准号: 7964134
• 负责人: Luigi Ferrucci
• 金额: $ 8.22万
• 依托单位: NATIONAL INSTITUTE ON AGING
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/7964134
• 关键词: Address; Age; Aging; Autopsy; Baltimore; Biological; Blood specimen; Cardiovascular Physiology; Cardiovascular system; Cells; Cessation of life; Clinic; Clinical Chemistry Tests; Cognition; Consent; Contracts; DNA; Data Set; Databases; Dementia; Disabled Persons; Disease; Drops; Enrollment; Event; Family; Health; Health Status; Healthcare; Hearing; Home visitation; House Call; Impaired cognition; Individual; Informed Consent; Kidney; Longitudinal Studies; Lung; Malignant Neoplasms; Metabolic; Nursing Homes; Outcome; Outcome Measure; Participant; Personality; Persons; Physical Function; Physiological; Plasma; Process; Research Ethics Committees; Resources; Schedule; Sensory; Specimen; Subgroup; Telephone; Telephone Interviews; Time; Update; Vision; Visit; design; disability; eligible participant; follow up assessment; follow-up; frailty; functional status; indexing; interest; mortality; programs; willingness

The activities conducted in the context of this project are summarized below: 1. Trace and update contact information on BLSA participants who are not currently coming to Baltimore for follow-up assessment, never formally dropped out from the study, and have been contacted (in person or over the telephone) at least once since 1990. 2. Make a telephone contact with the BLSA participants eligible for home visits to establish their status, their willingness to participate in the home visit program or, if not, in a telephone interview. 3. Create a formal process for tracking, contacting and following BLSA participants, and implement a process where traditional visits and home visits are integrated and serve complementary purposes. 4. In BLSA participants enrolled in the home visit program, conduct an extensive ascertainment of the health status, aimed at ascertaining multiple health-related outcomes (dementia, mobility limitation, ADL disability, frailty, CHD, cancer etc.). 5. In BLSA participants enrolled in the home visit program, collect a blood sample to be used for basic tests of clinical chemistry, DNA extraction and storage of cells, serum and plasma. 6. Provide participants and their families with a detailed description of the study, and obtain informed consent for participation, including consent for the use of previously collected biological specimens. 7. Create a database with all the tracking information and all information collected over the telephone interview and during in person home visits, maintaining full compatibility with the BLSA core database.

在该项目范围内开展的活动概述如下： 1.追踪并更新BLSA受试者的联系信息，这些受试者目前未来巴尔的摩进行随访评估，从未正式退出研究，并且自1990年以来至少联系过一次（亲自或通过电话）。 2.与有资格进行家访的BLSA参与者进行电话联系，以确定他们的状态，他们是否愿意参加家访计划，如果没有，则进行电话采访。 3.建立一个正式的程序，跟踪、联系和跟踪BLSA参与者，并实施一个程序，将传统访问和家访结合起来，发挥互补作用。 4.在BLSA参与者中，参加家访计划，进行广泛的健康状况调查，旨在确定多种健康相关结局（痴呆、行动受限、ADL残疾、虚弱、CHD、癌症等）。 5.在BLSA中，参加家访计划的参与者采集血液样本，用于临床化学、DNA提取和细胞、血清和血浆储存的基本检测。 6.向受试者及其家属提供研究的详细描述，并获得参与的知情同意书，包括同意使用之前采集的生物标本。 7.建立一个数据库，其中包括所有跟踪信息以及通过电话访谈和亲自家访收集的所有信息，并与劳工和社会事务局核心数据库保持完全兼容。