Administrative Core

管理核心 N2.4.1。行政核心的组织和运作。多学科/多机构的CCNE项目需要在复杂的翻译发展道路上整合连续的步骤，并需要非常高水平的互动来实现其目标。这就需要形成一个专门的和 经验丰富的行政和管理团队，并为这个团队分配适当的资源，以及时实现计划的里程碑。在我们目前的CCNE中，我们组建了一支如此出色的团队，拥有互补的专业领域。在CCNE-TR的过去3.5年里，这个团队已经正式成功地投入运营，我们将在当前的应用中继承这一被证明有效的结构。行政团队将由Sam Gambhir博士(核心 项目协调人)、王山(联席主任)、德米尔·阿金(副主任)和比莉·罗伯斯女士(方案协调员)。有关Gambhir、Wang和Akin的信息，请参见N2.3.2节。Akin博士目前一直担任CCNE-tr的副主任，并在过去的两年中担任行政核心领导，他将把这些专业知识带到CCNE-T，支持核心PI和共同PI。阿金博士是一位纳米医学科学家， 20多年的正规生物医学教育和超过8年的直接纳米医学和监督/管理技能来自他在普渡大学的工作经验，在那里他担任伯克纳米技术中心多学科和多研究者生物MEMS和纳米生物实验室(6个共享用户实验室)的经理。在BIRCK，他领导了合作小组内与生物医学相关的微生物技术研究业务，并在生物医学工程部担任了一个错误的职位，在那里他在诊断和治疗微/纳米设备、药物输送以及单分子生物医学纳米传感和成像领域进行了自己的跨学科研究。在过去两年里。Akin博士参与了CCNE-tr中心的整个活动，并一直与Gambhir博士(CCNE-tr的PI)合作，负责当前中心的行政管理。甘布希尔博士是一位杰出的领导者和管理者，如第N2.3.2节所述。上面。由于 鉴于CCNE U54机制的复杂性，以及对中心的多个管理、财政和科学方面的日常密切监督的必要性，Akin博士带来的管理技能将对中心活动的行政监督至关重要。在行政/预算/后勤方面，Billie Robles女士(计划协调员)自赠款开始以来一直担任这一职能，并在这一角色中积累了丰富的经验；她将继续担任相同的角色，并与Akin博士直接和非常密切的日常工作，使他能够确保中心的有效运作。 行政核心将从科学和管理/财政/后勤两个角度共同负责中心所有活动的日常同步运作。甘布希尔博士和王博士还将为行政核心提供中长期决策支持。

Administrative Core N2.4.1. Organization and Functioning of the Administrative Core. The multidisciplinary/multiinstitutional CCNE program requires integration of sequential steps in complex translational development pathways, and also very high levels of interaction to accomplish its goals. This necessitates the formation of a dedicated and highly experienced administrative and management team, and allocation of appropriate resources to this team, to achieve the program milestones in a timely manner. In our current CCNE, we have formed such an exceptional team with complementary areas of expertise. This team has been formally in operation, successfully, for the last 3.5 years of the CCNE-TR, and we will carry on this same proven-effective structure in the current application. The administrative team will be composed of Drs. Sam Gambhir (Core PI), Shan Wang (co-PI), Demir Akin (Deputy Director), and Ms. Billie Robles (Program Coordinator). For information on Drs Gambhir, Wang and Akin, please see section N2.3.2. Dr. Akin has currently been serving as the Deputy Director of the CCNE-TR, and as the Administrative Core leader for the last 2 years and he will bring this expertise to the CCNE-T in support of the Core PI and co-PI. Dr. Akin is a nanomedical scientist with over 20 years of formal education in biomedical sciences and more than 8 years of direct Nanomedicine and supervisory/managerial skills derived from his work experience at Purdue University where he served as the Manager of the multi-disciplinary and multi-investigator BioMEMS and Nanobio Laboratories (6 shared user labs) at the Birck Nanotechnology Center. At Birck, he directed the biomedically relevant micronanotechnology research operations within the collaborating groups, and also held a faulty appointment in the Biomedical Engineering Department where he performed his own interdisciplinary research in the areas of diagnostic and therapeutic micro/nano devices, drug delivery and single molecule biomedical nanosensing and imaging. During the past two years. Dr. Akin has become involved with the entire CCNE-TR center activities and has been working with Dr. Gambhir (PI of CCNE-TR) in administration and management of the current center. Dr. Gambhir is an exceptional leader and manager as outlined in section N2.3.2. above. Due to the complexity of the CCNE U54 mechanism, and the necessity for daily, close oversight of the multiple managerial, fiscal and scientific aspects of the center, the administrative skills that Dr. Akin brings will be essential for the administrative oversight of center activities. On the administrative/budgetary/logistical front, Ms, Billie Robles (Program Coordinator) has been serving this function since the beginning of the grant, and has gained tremendous experience in this role; she will continue to serve in the same role and work directly and very closely on a daily basis with Dr, Akin to enable him to assure effective operation of the center. Together the administrative core will be responsible for the daily in-synch operations of all center activities from both a scientific and managerial/fiscal/logistical perspective. Drs. Gambhir and Wang will also provide mid- to long-term decision support to the Administrative Core.