Training Program for Medical Scientists

描述（由申请人提供）：本申请要求继续支持南卡罗来纳医科大学的医学科学家培训计划。目标是培养选择终身从事生物医学研究的内科科学家，跨越基础科学和临床科学之间的接口。该项目成立于1980年，并稳步发展到目前的59名学生。迄今为止，MSTP毕业生的职业成果包括教授2人，副教授3人，助理教授12人，从事工业研究6人，私人执业14人，仍在培训30人，职位未知1人。在过去的5年里，该项目显著增加了申请者的规模和水平，部分原因在于一项全国性的招聘计划，该计划包括广泛的个人联系和跟踪，向MCAT分数为100 - 32的个人分发招聘光盘，不断更新的网站，以及积极招聘优秀的候选人和招聘奖学金。我们的MSTP申请人和毕业生的质量和数量的增长反映了MUSC对该计划的杰出承诺，以及其整体研究和培训环境的实质性增长和发展，并且是每年要求从6个增加到8个职位的基础。我们的MSTP是按照两年（医学院）、三到四年（研究生院）和两年（医学院）的经典范例设计的。除了严格的基础科学研究培训外，该计划还增加了独特的机会，通过转化科学诊所，转化医学研讨会和在GCRC的一个月来获得临床和转化研究的经验。下一阶段的目标是：(1)在MUSC生物医学研究重点的主要领域提供严格的培训，由一个高度协作的核心团队领导，他们在研究和指导方面取得了卓越的成就；(2)提供精心设计的灵活课程，培养学生在基础研究和临床研究中的独立思考能力；(3)在具有挑战性的互动环境中进行培训，包括基础科学、临床科学和转化科学，以及持续的技能获取和专业发展活动；(4)实施一个扩展的正式评估计划，包括定量和定性数据、有意义的比较和多种信息来源；(5)接受外部咨询委员会的客观建议和指导，该委员会的活动包括审查项目成就，评估项目过程和结果，并就未来方向提出建议。相关性：该MST项目的毕业生将接受严格的基础科学培训，并接触临床和转化研究。他们将成为未来能够进行基础研究和以患者为导向的研究的学术医师科学家骨干的一部分。他们将能够连接基础科学和临床科学，并为预防和治疗人类疾病带来新的和新颖的方法。

DESCRIPTION (provided by applicant): This application requests continued support of the Medical Scientist Training Program at the Medical University of South Carolina. The goal is to produce physician-scientists who choose a lifelong career in biomedical research spanning the interface between the basic and clinical sciences. The program was founded in 1980 and has steadily grown to its current size of 59 students. Career outcomes of MSTP graduates to date include 2 professors holding endowed chairs, 3 associate professors, 12 assistant professors, 6 conducting research in industry, 14 in private practice, 30 still in training, and 1 position unknown. During the past 5-year period the program has significantly increased the size and caliber of the applicant pool due in part to a national recruitment plan that incorporates extensive personal contact and follow-up, distribution of a recruitment CD to individuals with MCAT scores >32, a continuously updated web site, and aggressive recruitment of outstanding candidates with recruitment scholarships. The growth in quality and quantity of our MSTP applicants and matriculants reflects MUSC's outstanding commitment to the program, as well as substantive growth and development in its overall research and training environment, and is the basis for a requested increase from 6 to 8 positions per year. Our MSTP is designed along the classical paradigm of two years (medical school), three to four years (graduate school), and two years (medical school). In addition to rigorous basic science research training, the program has added unique opportunities to gain experiences in clinical and translational research through the Translational Sciences Clinic, Translational Medicine Seminars, and a Month in the GCRC. The objectives for the next phase are to: (1) provide rigorous training in major areas of biomedical research emphasis at MUSC led by a highly collaborative core group of faculty with exceptional records of accomplishment in research and mentoring; (2) offer a carefully designed yet flexible curriculum that trains students to think independently in both basic research and clinical investigation; (3) conduct the training in a challenging, interactive environment that embraces basic, clinical and translational sciences, and on-going skills acquisition and professional development activities; (4) implement an expanded formal evaluation plan that incorporates quantitative and qualitative data, meaningful comparisons, and multiple sources of information; and (5) receive objective advice and guidance from an External Advisory Committee whose activities include reviewing program accomplishments, evaluating program processes and outcomes, and advising on future directions. RELEVANCE: Graduates of this MST program will have received rigorous training in the basic sciences and exposure to clinical and translational research. They will be part of the future cadre of academic physician-scientists able to conduct both basic and patient oriented research. They will be capable of bridging the basic and clinical sciences and bring new and novel approaches for the prevention and treatment of human diseases.