Training Program for Medical Scientists

描述（由申请人提供）：本申请要求继续支持南卡罗来纳州医科大学的医学科学家培训计划。其目标是培养选择终身从事生物医学研究的医生科学家，这些研究跨越基础科学和临床科学之间的界面。该计划成立于1980年，并已稳步增长到目前的59名学生的规模。到目前为止，MSTP毕业生的职业成果包括2名教授担任捐赠椅子，3名副教授，12名助理教授，6名从事工业研究，14名私人执业，30名仍在培训，1名职位未知。在过去的5年期间，该计划显着增加了申请人池的规模和口径，部分原因是国家招聘计划，其中包括广泛的个人联系和后续行动，向MCAT分数>32的个人分发招聘CD，不断更新的网站，以及积极招聘优秀候选人并提供招聘奖学金。我们MSTP申请人和预科生的质量和数量的增长反映了MUSC对该计划的杰出承诺，以及其整体研究和培训环境的实质性增长和发展，并且是每年从6个职位增加到8个职位的基础。我们的MSTP是按照两年（医学院），三到四年（研究生院）和两年（医学院）的经典范例设计的沿着。除了严格的基础科学研究培训，该计划还增加了独特的机会，通过转化科学诊所，转化医学研讨会和GCRC的一个月来获得临床和转化研究的经验。下一阶段的目标是：（1）在MUSC的生物医学研究重点的主要领域提供严格的培训，由具有研究和指导成就的卓越记录的教师领导的高度合作的核心小组;（2）提供精心设计但灵活的课程，培养学生在基础研究和临床研究中独立思考;（3）在具有挑战性的互动环境中开展培训，包括基础科学、临床科学和转化科学，以及正在进行的技能获取和专业发展活动;（4）实施扩大的正式评估计划，其中包括定量和定性数据、有意义的比较和多种信息来源;以及（5）从外部咨询委员会获得客观的建议和指导，该委员会的活动包括审查项目成果、评估项目过程和成果，以及就未来方向提供建议。相关性：该MST计划的毕业生将接受基础科学的严格培训，并接触临床和转化研究。他们将成为未来能够进行基础和面向患者的研究的学术医生科学家骨干的一部分。它们将能够连接基础科学和临床科学，为预防和治疗人类疾病带来新的和新颖的方法。

DESCRIPTION (provided by applicant): This application requests continued support of the Medical Scientist Training Program at the Medical University of South Carolina. The goal is to produce physician-scientists who choose a lifelong career in biomedical research spanning the interface between the basic and clinical sciences. The program was founded in 1980 and has steadily grown to its current size of 59 students. Career outcomes of MSTP graduates to date include 2 professors holding endowed chairs, 3 associate professors, 12 assistant professors, 6 conducting research in industry, 14 in private practice, 30 still in training, and 1 position unknown. During the past 5-year period the program has significantly increased the size and caliber of the applicant pool due in part to a national recruitment plan that incorporates extensive personal contact and follow-up, distribution of a recruitment CD to individuals with MCAT scores >32, a continuously updated web site, and aggressive recruitment of outstanding candidates with recruitment scholarships. The growth in quality and quantity of our MSTP applicants and matriculants reflects MUSC's outstanding commitment to the program, as well as substantive growth and development in its overall research and training environment, and is the basis for a requested increase from 6 to 8 positions per year. Our MSTP is designed along the classical paradigm of two years (medical school), three to four years (graduate school), and two years (medical school). In addition to rigorous basic science research training, the program has added unique opportunities to gain experiences in clinical and translational research through the Translational Sciences Clinic, Translational Medicine Seminars, and a Month in the GCRC. The objectives for the next phase are to: (1) provide rigorous training in major areas of biomedical research emphasis at MUSC led by a highly collaborative core group of faculty with exceptional records of accomplishment in research and mentoring; (2) offer a carefully designed yet flexible curriculum that trains students to think independently in both basic research and clinical investigation; (3) conduct the training in a challenging, interactive environment that embraces basic, clinical and translational sciences, and on-going skills acquisition and professional development activities; (4) implement an expanded formal evaluation plan that incorporates quantitative and qualitative data, meaningful comparisons, and multiple sources of information; and (5) receive objective advice and guidance from an External Advisory Committee whose activities include reviewing program accomplishments, evaluating program processes and outcomes, and advising on future directions. RELEVANCE: Graduates of this MST program will have received rigorous training in the basic sciences and exposure to clinical and translational research. They will be part of the future cadre of academic physician-scientists able to conduct both basic and patient oriented research. They will be capable of bridging the basic and clinical sciences and bring new and novel approaches for the prevention and treatment of human diseases.