CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCH

CTSA 儿科研究基础设施

• 批准号: 8366102
• 负责人: JULIANNE L IMPERATO-MCGINLEY
• 金额: $ 147.33万
• 依托单位: WEILL MEDICAL COLL OF CORNELL UNIV
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-06-01 至 2012-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8366102
• 关键词: Center for Translational Science Activities; Clinical Sciences; Pediatric Research; Research Infrastructure

This subproject represents an estimate of the percentage of the CTSA funding that is being utilized for a broad area of research (AIDS research, pediatric research, or clinical trials). The Total Cost listed is only an estimate of the amount of CTSA infrastructure going towards this area of research, not direct funding provided by the NCRR grant to the subproject or subproject staff. The development of the Clinical and Translational Science Center (CTSC) fulfills the mission to advance the nation's clinical research enterprise of moving translational research seamlessly from bench to bedside and to the community. The Center represents our vision to deliver the vast knowledge of recent biomedical advances to clinical application for meaningful healthcare practices and to nurture multidisciplinary translational research education and training. The CTSC has been designed to capture the collective of intellectual capital, cutting-edge resources and diverse patient base of partnering institutions and to integrate them for maximum translational research benefits. As lead institution, Weill Cornell Medical Center (WCMC) will serve as an academic home through which essential resources, technological tools and education programs can be efficiently shared and managed. The partner institutions comprising the CTSC are also neighbors located on York Avenue. Within the immediate area are: WCMC, including Weill Cornell Medical College, Weill Cornell Graduate School of Medical Sciences and the Weill Cornell Campus of NewYork-Presbyterian Hospital; Memorial Sloan-Kettering Cancer Center; and the Hospital for Special Surgery. In close proximity on the East Side of Manhattan are: Hunter College School of Nursing, Hunter College Center for the Study of Gene Structure and Function/Research Center for Minority Institutions and the Cornell University Cooperative Extension in New York City. The resulting cluster of institutions forms a unique and cohesive biomedical complex fulfilling the NIH roadmap initiative of breaking-down institutional and disciplinary silos to accelerate translational research. Separately, the partner institutions are superb centers of intellectual and academic excellence, thus their integration into the CTSC will harness their distinctive characteristics and hasten clinical and translational research breakthroughs for improved patient care. The trans-institutional governance structure outlined in this application and supplemented by a comprehensive systems-based evaluation process are important in overcoming bureaucracies and barriers. New initiatives were sculpted and programs with a history of collaboration between partners were broadened and restructured. The key elements of the CTSC are: 1) development of novel clinical and translational methodologies; 2) pilot and collaborative translational and clinical studies; 3) biomedical informatics; 4) design, biostatistics and clinical research ethics; 5) regulatory knowledge and support; 6) participant and clinical interaction resources; 7) community engagement and research; 8) translational technologies and resources; 9) research education, training and career development; and 10) other program functions. The CTSC is a vital link between the academic, research and clinical practice functions of partner institutions and will provide an important continuum in translational research.

该子项目是对CTSA供资的百分比的估计， 用于广泛的研究领域（艾滋病研究，儿科研究，或 临床试验）。 列出的总成本仅为CTSA金额的估算 基础设施走向这一领域的研究，而不是直接提供资金， 向子项目或子项目工作人员提供NCRR补助金。 临床和转化科学中心（CTSC）的发展实现了推进国家临床研究企业的使命，将转化研究从实验室无缝地转移到床边和社区。该中心代表了我们的愿景，即为有意义的医疗实践提供最新生物医学进展的大量知识，并培养多学科转化研究教育和培训。CTSC旨在获取合作机构的智力资本，尖端资源和多样化患者基础的集体，并将其整合以实现最大的转化研究效益。作为牵头机构，威尔康奈尔医学中心（WCMC）将作为一个学术之家，通过它可以有效地共享和管理必要的资源，技术工具和教育计划。组成反恐服务中心的伙伴机构也毗邻约克大道。在直接区域内有：WCMC，包括威尔康奈尔医学院、威尔康奈尔医学研究生院和纽约长老会医院威尔康奈尔校区;纪念斯隆-凯特琳癌症中心;和特殊外科医院。在曼哈顿的东侧有：亨特学院护理学院，亨特学院基因结构和功能研究中心/少数民族机构研究中心和康奈尔大学合作推广在纽约市。由此产生的机构集群形成了一个独特而有凝聚力的生物医学综合体，实现了打破机构和学科孤岛以加速转化研究的NIH路线图倡议。另外，合作机构是智力和学术卓越的卓越中心，因此它们融入CTSC将利用其独特的特点，加快临床和转化研究的突破，以改善患者护理。本申请中概述的跨机构治理结构，加上全面的系统评价程序，对于克服官僚主义和障碍十分重要。制定了新的倡议，扩大和调整了伙伴之间有合作历史的方案。CTSC的关键要素是：1）开发新的临床和转化方法; 2）试点和合作的转化和临床研究; 3）生物医学信息学; 4）设计，生物统计学和临床研究伦理学; 5）法规知识和支持; 6）参与者和临床互动资源; 7）社区参与和研究; 8）转化技术和资源; 8）生物医学信息学; 9）生物医学信息学; 10）生物医学信息学; 11）生物统计学和临床研究伦理学; 12）生物医学信息学; 13）生物医学信息学; 14）生物医学信息学; 15）生物医学信息学; 16）生物医学信息学; 17）生物医学信息学; 18）生物医学信息学; 19 9）研究教育，培训和职业发展;和10）其他程序功能。CTSC是合作机构的学术，研究和临床实践职能之间的重要联系，并将提供转化研究的重要连续体。