Clinical and Translational Science Center (UL1)

临床和转化科学中心 (UL1)

• 批准号: 8140982
• 负责人: JULIANNE L IMPERATO-MCGINLEY
• 金额: $ 15.29万
• 依托单位: WEILL MEDICAL COLL OF CORNELL UNIV
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-23 至 2012-09-22
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8140982
• 关键词: Clinical; Translational; Science; Center; UL1

The development of the Clinical and Translational Science Center (CTSC) fulfills the mission to advance the nation's clinical research enterprise of moving translational research seamlessly from bench to bedside and to the community. The Center represents our vision to deliver the vast knowledge of recent biomedical advances to clinical application for meaningful healthcare practices andto nurture multidisciplinary translational research education and training. The CTSC has been designed to capture the collective of intellectual capital, cutting-edge resources and diverse patient base of partnering institutions and to integrate them for maximum translational research benefits. As lead institution, Weill Cornell Medical Center (WCMC) will serve as an academic home through which essential resources, technological tools and education programs can be efficiently shared and managed. The partner institutions comprising the CTSC are also neighbors located on York Avenue. Within the immediate area are: WCMC, including Weill Cornell Medical College, Weill Cornell Graduate School of Medical Sciences and the Weill Cornell Campus of NewYork-Presbyterian Hospital; Memorial Sloan-Kettering Cancer Center; and the Hospital for Special Surgery. In close proximity on the East Side of Manhattan are: Hunter College School of Nursing, Hunter College Center for the Study of Gene Structure and Function/Research Center for Minority Institutions and the Cornell University Cooperative Extension in New York City. The resulting cluster of institutions forms a unique and cohesive biomedical complex fulfilling the NIH roadmap initiative of breaking-down institutional and disciplinary silos to accelerate translational research. Separately, the partner institutions are superb centers of intellectual and academic excellence, thus their integration into the CTSC will harness their distinctive characteristics and hasten clinical and translational research breakthroughs for improved patient care. The trans-institutional governance structure outlined in this application and supplemented by a comprehensive systems-based evaluation process are important in overcoming bureaucracies and barriers. New initiatives were sculpted and programs with a history of collaboration between partners were broadened and restructured. The key elements of the CTSC are: 1) development of novel clinical and translational methodologies; 2) pilot and collaborative translational and clinical studies; 3) biomedical informatics; 4) design, biostatistics and clinical research ethics; 5) regulatory knowledge and support; 6) participant and clinical interaction resources; 7) community engagement and research; 8) translational technologies and resources; 9) research education, training and career development; and 10) other program functions. The CTSC is a vital link between the academic, research and clinical practice functions of partner institutions and will provide an important continuum in translational research.

临床和转化科学中心（CTSC）的发展履行使命 国家的临床研究企业，将转化研究从实验室无缝地转移到床边， 社区该中心代表了我们的愿景，提供最新生物医学进展的大量知识， 临床应用于有意义的医疗实践，并培养多学科转化研究 教育培训CTSC的设计旨在捕捉集体的智力资本，尖端 资源和合作机构的多样化患者基础，并将其整合， 研究效益。 作为牵头机构，威尔康奈尔医学中心（WCMC）将作为一个学术之家， 重要的资源、技术工具和教育方案可以得到有效的共享和管理。的 包括CTSC的伙伴机构也位于约克大道的邻居。在邻近区域内 是：WCMC，包括威尔康奈尔医学院，威尔康奈尔医学科学研究生院和 纽约长老会医院威尔康奈尔校区;纪念斯隆-凯特琳癌症中心;以及 特殊外科医院。在曼哈顿的东侧附近有：亨特学院 护理，亨特学院基因结构和功能研究中心/少数民族研究中心 机构和康奈尔大学合作推广在纽约市。由此产生的集群 机构形成了一个独特的和有凝聚力的生物医学复合体，实现了NIH的路线图倡议，打破了 机构和学科筒仓，以加速转化研究。另外，伙伴机构包括 一流的智力和学术卓越中心，因此，他们融入CTSC将利用他们的 独特的特点和加速临床和转化研究的突破，以改善病人护理。 本申请中概述的跨机构治理结构， 基于系统的评价进程对于克服官僚主义和障碍十分重要。 制定了新的倡议，扩大了合作伙伴之间有合作历史的项目 和重组。CTSC的关键要素是：1）开发新的临床和翻译 方法学; 2）试点和协作转化和临床研究; 3）生物医学信息学; 4）设计， 生物统计学和临床研究伦理; 5）法规知识和支持; 6）参与者和临床 互动资源; 7）社区参与和研究; 8）转化技术和资源; 9） 研究教育，培训和职业发展;和10）其他程序功能。CTSC是一个重要的环节， 合作机构的学术，研究和临床实践职能之间的联系，并将提供重要的 翻译研究中的连续体。