权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

A Program of Research and Mentorship on Alcoholism and Co-occuring Disorders

关于酗酒和并发疾病的研究和指导计划

基本信息

批准号：
8133156
负责人：
Michael Parks Bogenschutz
金额：
$ 17.67万
依托单位：
UNIVERSITY OF NEW MEXICO
依托单位国家：
美国
项目类别：
财政年份：
2007
资助国家：
美国
起止时间：
2007-09-20 至 2013-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8133156
关键词：
Alcohol dependence Alcoholism Anxiety Disorders Benzodiazepines Clinical Clinical Research Clinical Trials Clinical Trials Network Comorbidity Development Diagnosis Disease Disulfiram Doctor of Philosophy Educational Activities Faculty Funding Goals Grant Image Individual Learning Medical Students Mental disorders Mentally Ill Persons Mentors Mentorship Methodology Mid-Career Clinical Scientist Award (K24)Modeling National Institute of Drug Abuse New Mexico Patients Persons Population Psychiatry Publishing Research Research Activity Research Infrastructure Research Personnel Research Project Grants Research Training Resources Substance abuse problem Training and Education United States National Institutes of Health Universities addiction alcohol use disorder base cost effective therapy experience graduate student medical schools member next generation novel novel strategies problem drinker programs

项目摘要

DESCRIPTION (provided by applicant): I want to achieve two goals in the next 5 years through this K24 award: to deepen my own program of research, focusing on the treatment of dually diagnosed persons, and to facilitate the development of a more extensive program of clinical research in addictions at the University of New Mexico by helping to develop the next generation of clinical researchers at our facilities. My research to date has focused on clinical trials, mutual help approaches for the dually diagnosed, and other research on comorbidity and 12-step programs. Current grant funding includes an R01 grant to study the efficacy of a modified 12-step facilitation therapy for seriously mentally ill alcoholics (R01AA015419), and a U10 grant for the Southwest Node of the NIDA Clinical Trials Network (U10DA1533). I have extensive research mentoring experience with junior faculty, fellows, psychiatric residents, Ph.D. candidates, and medical students. Institutional resources for research and mentorship in addictions include faculty, trainees, and infrastructure at the UNM Center on Alcoholism, Substance Abuse, and Addiction, the School of Medicine, and the MIND Imaging Center, as well as diverse and accessible clinical populations. Six Specific Aims are proposed. The research Specific Aims are 1) To leam methodologies critical to the development of programmatic clinical research on comorbid conditions; 2) To conduct preliminary studies supporting the development of a novel pharrnacotherapeutic approach for individuals with alcohol dependence and co-occurring anxiety disorders, involving the co-administration of disulfiram and a benzodiazepine a 16-week model of treatment; 3) To develop, submit, and obtain funding for an R01 grant studying this pharrnacotherapeutic approach. The mentorship Specific Aims are 4) to mentor at least 3 junior faculty members to the point of submitting proposals for independent NIH funding; 5) to provide research training to at least three addiction psychiatry fellows, graduate students, or psychiatry residents per year through participation in ongoing research projects; and 6) To provide ongoing training and education to a broader group through a variety of lower-intensity mentorship and educational activities. Relevance: Mental illness and alcoholism frequently occur together, resulting in disproportionate suffering and cost. There is a need for better understanding and more effective treatments for these conditions. This grant supports the development of new research approaches and new researchers in this important field.

描述（由申请人提供）：我想通过这个K24奖项在未来5年实现两个目标：深化我自己的研究项目，专注于双重诊断患者的治疗，并通过帮助培养下一代临床研究人员来促进新墨西哥大学更广泛的成瘾临床研究项目的发展。到目前为止，我的研究主要集中在临床试验、双重诊断的互助方法，以及其他关于合并症和12步治疗计划的研究。目前的拨款包括一项R01拨款，用于研究改良的12步促进疗法的疗效