Decision Making in Biosurveillance

生物监测决策

• 批准号: 8137928
• 负责人: MICHAEL MATTHEW WAGNER
• 金额: $ 60.2万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-09-30 至 2013-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8137928
• 关键词: Bioterrorism; Computer software; Consultations; Data; Data Analyses; Decision Analysis; Decision Making; Decision Modeling; Decision Support Systems; Differential Diagnosis; Disease; Disease Outbreaks; Drug Formulations; Economic Models; Economics; Epidemiologist; Event; Face; Figs - dietary; Health; Investigation; Libraries; Modeling; Morbidity - disease rate; Output; Policies; Public Health; Publishing; Research; Risk; Science; Speed; State or Local Health Department; System; Techniques; Time; Uncertainty; Work; base; improved; middle column; mortality; pressure; response; surveillance data; tool

DESCRIPTION (provided by applicant): The long-term objective of this research is to advance the use of decision analysis in biosurveillance. The disease surveillance staff in a health department face an increasing number of high-stakes decisions under uncertainty and time pressure. This situation is in part due to the threat of bioterrorism and emerging diseases and in part a result of new surveillance systems they have constructed. These systems collect less diagnostically precise--but earlier--surveillance data in an effort to detect disease outbreaks as early as possible. The specific aims of the research are to (1) construct decision analyses of representative bio-surveillance decision problems using standard decision analytic techniques, and (2) deploy the underlying decision models in a decision-support system for analysts and epidemiologists. The research has the potential to improve the speed and efficacy of public health response to outbreaks and thereby potentially reduce morbidity and mortality. The research also has the potential to increase the efficiency of bio-surveillance systems by providing a basis for rational setting of alarm thresholds.

描述（由申请人提供）： 本研究的长期目标是促进决策分析在生物监测中的应用。在不确定性和时间压力下，卫生部门的疾病监测人员面临着越来越多的高风险决策。造成这种情况的部分原因是生物恐怖主义和新出现的疾病的威胁，部分原因是它们建立了新的监测系统。这些系统收集的诊断准确性较低但较早的监测数据，以尽可能早地发现疾病爆发。 研究的具体目标是（1）使用标准决策分析技术构建具有代表性的生物监测决策问题的决策分析，以及（2）在分析师和流行病学家的决策支持系统中部署底层决策模型。 这项研究有可能提高公共卫生应对疫情的速度和效力，从而有可能降低发病率和死亡率。这项研究还可能通过为合理设定警报阈值提供依据来提高生物监测系统的效率。

项目成果

The economic value of a quadrivalent versus trivalent influenza vaccine.

• DOI: 10.1016/j.vaccine.2012.10.025
• 发表时间: 2012-12-14
• 期刊: VACCINE
• 影响因子: 5.5
• 作者: Lee, Bruce Y.;Bartsch, Sarah M.;Willig, Alyssa M.
• 通讯作者: Willig, Alyssa M.

Probabilistic, Decision-theoretic Disease Surveillance and Control.

• DOI: 10.5210/ojphi.v3i3.3798
• 发表时间: 2011-01-01
• 期刊: Online journal of public health informatics
• 作者: Wagner, Michael;Tsui, Fuchiang;Potter, Margaret
• 通讯作者: Potter, Margaret

A method for estimating from thermometer sales the incidence of diseases that are symptomatically similar to influenza.

• DOI: 10.1016/j.jbi.2013.02.003
• 发表时间: 2013-06
• 期刊: Journal of biomedical informatics
• 影响因子: 4.5
• 作者: Villamarín R;Cooper G;Wagner M;Tsui FC;Espino JU
• 通讯作者: Espino JU

Would school closure for the 2009 H1N1 influenza epidemic have been worth the cost?: a computational simulation of Pennsylvania.

2009年H1N1流感流行的学校关闭是否值得？：宾夕法尼亚州的计算模拟。

• DOI: 10.1186/1471-2458-11-353
• 发表时间: 2011-05-20
• 期刊: BMC public health
• 影响因子: 4.5
• 作者: Brown ST;Tai JH;Bailey RR;Cooley PC;Wheaton WD;Potter MA;Voorhees RE;LeJeune M;Grefenstette JJ;Burke DS;McGlone SM;Lee BY
• 通讯作者: Lee BY

Cost-effectiveness of adjuvanted versus nonadjuvanted influenza vaccine in adult hemodialysis patients.

成人血液透析患者中​​佐剂流感疫苗与非佐剂流感疫苗的成本效益。

• DOI: 10.1053/j.ajkd.2010.12.016
• 发表时间: 2011
• 期刊: American journal of kidney diseases : the official journal of the National Kidney Foundation
• 作者: Lee,BruceY;Stalter,RandyM;Bacon,KristinaM;Tai,JulieHY;Bailey,RachelR;Zimmer,ShantaM;Wagner,MichaelM
• 通讯作者: Wagner,MichaelM