Established Investigator Award in Cancer Prevention and Control

设立癌症预防和控制研究者奖

基本信息

批准号：
8098685
负责人：
THOMAS L VAUGHAN
金额：
$ 15.4万
依托单位：
FRED HUTCHINSON CANCER RESEARCH CENTER
依托单位国家：
美国
项目类别：
财政年份：
2007
资助国家：
美国
起止时间：
2007-07-23 至 2012-08-05
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8098685
关键词：
Adoption Area Award Barrett Esophagus Barrett&apos s Adenocarcinoma Biological Biology Biometry Cancer Control Case-Control Studies Communities Computer software Data Data Analyses Developing Countries Development Diagnosis Discipline Disease Environmental Epidemiology Epidemiology Equilibrium Esophageal Adenocarcinoma Etiology Explosion Faculty Fred Hutchinson Cancer Research Center Funding Genetic Determinism Genetic screening method Goals Grant Health Incidence Institution International Knowledge Life Style Malignant - descriptor Malignant Neoplasms Mentors Molecular Molecular Genetics National Institute of Diabetes and Digestive and Kidney Diseases Nature Persons Population Population Heterogeneity Postdoctoral Fellow Prevention Principal Investigator Public Health Research Research Activity Research Personnel Research Project Grants Role Screening procedure Senior Scientist Award Specimen Students Time Tissues Training Universities Washington Woman Work aging population base cancer epidemiology cancer prevention design essays graduate student lecturer men population based pre-doctoral programs success virtual

项目摘要

DESCRIPTION (provided by applicant): The K05 award will provide Dr. Thomas L Vaughan with protected time (30% FTE) to pursue key research questions related to the etiology and prevention of esophageal adenocarcinoma, a cancer that has increased over six-fold in incidence over three decades. It will also provide for protected time (20% FTE) to expand his already extensive mentoring activities of students and other junior investigators at the University of Washington (UW) and the Fred Hutchinson Cancer Research Center (FHCRC). Dr. Vaughan was one of the founders of the Barrett's and Esophageal Adenocarcinoma Consortium (BEACON), an international consortium of over 30 investigators representing 16 studies, supported in part by NCI and NIDDK, and was elected as the first Chair of the Steering Committee. The research aspects of this award will be conducted in the context of the BEACON, and consist of: i) continued analyses of data and tissue collected as part of a community-based case-control studies of incident Barrett's for which Dr. Vaughan was PI, ii) pooled analyses of data from multiple population-based studies carried out by BEACON investigators, and iii) development of new collaborative research projects within BEACON that take advantage of the diverse populations represented, and existing banks of well-characterized tissues. Dr. Vaughan has a well-established track record of mentoring graduate students and postdoctoral fellows, as well as junior faculty in Epidemiology and related disciplines. He was Co-director of the Environmental Epidemiology Training Grant from 1990-2006; in 2005 he assumed responsibility as Director of the NCI-funded Cancer Epidemiology and Biostatistics Training Grant (T32CA09168). He is a frequent guest lecturer in established epidemiology courses, and has served on 23 masters thesis committees and 20 doctoral dissertation committees. Expanded mentoring activities on the K05 will include: i) those associated with his responsibilities on the training grant, ii) his ongoing mentoring of other trainees from Epidemiology and related departments, and junior faculty across public health disciplines at the UW and FHCRC, and iii) two new pre- or post-doctoral students working directly on K05-associated research activities.

描述（由申请人提供）：K05奖将为托马斯·沃恩博士提供受保护的时间（30％FTE），以追求与病因学和预防食管腺癌有关的关键研究问题，该癌症在三十年中的发病率增加了六倍以上。它还将提供受保护的时间（20％FTE），以扩大华盛顿大学（UW）和Fred Hutchinson Cancer Research Center（FHCRC）的学生和其他初级调查人员的广泛指导活动。 Vaughan博士是Barrett's和食管腺癌财团（Beacon）的创始人之一，该联盟（Beacon）是一个由30多名代表16项研究的国际财团，部分由NCI和NIDDK支持，并被当选为指导委员会的第一任主席。该奖项的研究方面将在信标的背景下进行，并包括：i）继续分析收集的数据和组织，作为基于社区的病例对照巴雷特的一部分，沃恩博士是PI，PI，ii）汇总了对Beacon研究人员和III范围内的多个人群研究范围的数据分析，该研究的范围是Beacon研究人员，以及III范围内的研究，该项目的能力，该项目的发展，III范围的范围，III范围的范围，涉及Beacon Internal of Beacon研究，涉及Beacon研究的范围。特征良好的组织。沃恩博士在指导研究生和博士后研究员以及流行病学和相关学科的初级教职员工方面拥有良好的记录。他是1990 - 2006年环境流行病学培训赠款的联合主任； 2005年，他担任NCI资助的癌症流行病学和生物统计学培训补助金（T32CA09168）的责任。他是建立流行病学课程的常客讲师，并曾在23个硕士论文委员会和20个博士学位论文委员会任职。 Expanded mentoring activities on the K05 will include: i) those associated with his responsibilities on the training grant, ii) his ongoing mentoring of other trainees from Epidemiology and related departments, and junior faculty across public health disciplines at the UW and FHCRC, and iii) two new pre- or post-doctoral students working directly on K05-associated research activities.