Established Investigator Award in Cancer Prevention and Control

设立癌症预防和控制研究者奖

• 批准号: 7629722
• 负责人: THOMAS L VAUGHAN
• 金额: $ 15.36万
• 依托单位: FRED HUTCHINSON CANCER RESEARCH CENTER
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-07-23 至 2012-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7629722
• 关键词: Adoption; Area; Award; Barrett Esophagus; Biological; Biology; Biometry; Case-Control Studies; Communities; Computer software; Data; Data Analyses; Developed Countries; Developing Countries; Development; Diagnosis; Discipline; Disease; Environmental Epidemiology; Epidemiology; Equilibrium; Esophageal Adenocarcinoma; Etiology; Explosion; Faculty; Fred Hutchinson Cancer Research Center; Funding; Genetic Determinism; Genetic screening method; Goals; Grant; Health; Incidence; Institution; International; Knowledge; Life Style; Malignant - descriptor; Malignant Neoplasms; Mentors; Molecular; Molecular Genetics; National Institute of Diabetes and Digestive and Kidney Diseases; Nature; Persons; Population; Population Heterogeneity; Postdoctoral Fellow; Prevention; Principal Investigator; Public Health; Research; Research Activity; Research Personnel; Research Project Grants; Role; Screening procedure; Senior Scientist Award; Specimen; Students; Time; Tissues; Training; Universities; Washington; Woman; Work; aging population; base; cancer epidemiology; cancer prevention; design; essays; graduate student; lecturer; men; population based; programs; success; virtual

DESCRIPTION (provided by applicant): The K05 award will provide Dr. Thomas L Vaughan with protected time (30% FTE) to pursue key research questions related to the etiology and prevention of esophageal adenocarcinoma, a cancer that has increased over six-fold in incidence over three decades. It will also provide for protected time (20% FTE) to expand his already extensive mentoring activities of students and other junior investigators at the University of Washington (UW) and the Fred Hutchinson Cancer Research Center (FHCRC). Dr. Vaughan was one of the founders of the Barrett's and Esophageal Adenocarcinoma Consortium (BEACON), an international consortium of over 30 investigators representing 16 studies, supported in part by NCI and NIDDK, and was elected as the first Chair of the Steering Committee. The research aspects of this award will be conducted in the context of the BEACON, and consist of: i) continued analyses of data and tissue collected as part of a community-based case-control studies of incident Barrett's for which Dr. Vaughan was PI, ii) pooled analyses of data from multiple population-based studies carried out by BEACON investigators, and iii) development of new collaborative research projects within BEACON that take advantage of the diverse populations represented, and existing banks of well-characterized tissues. Dr. Vaughan has a well-established track record of mentoring graduate students and postdoctoral fellows, as well as junior faculty in Epidemiology and related disciplines. He was Co-director of the Environmental Epidemiology Training Grant from 1990-2006; in 2005 he assumed responsibility as Director of the NCI-funded Cancer Epidemiology and Biostatistics Training Grant (T32CA09168). He is a frequent guest lecturer in established epidemiology courses, and has served on 23 masters thesis committees and 20 doctoral dissertation committees. Expanded mentoring activities on the K05 will include: i) those associated with his responsibilities on the training grant, ii) his ongoing mentoring of other trainees from Epidemiology and related departments, and junior faculty across public health disciplines at the UW and FHCRC, and iii) two new pre- or post-doctoral students working directly on K05-associated research activities.

描述（由申请人提供）：K05 奖将为 Thomas L Vaughan 博士提供受保护的时间（30% FTE），以研究与食管腺癌的病因学和预防相关的关键研究问题，食管腺癌的发病率在三十年来增加了六倍多。它还将提供受保护的时间（20% FTE），以扩大他对华盛顿大学 (UW) 和 Fred Hutchinson 癌症研究中心 (FHCRC) 的学生和其他初级研究人员的广泛指导活动。 Vaughan 博士是 Barrett 和食管腺癌联盟 (BEACON) 的创始人之一，该联盟是一个由代表 16 项研究的 30 多名研究人员组成的国际联盟，得到 NCI 和 NIDDK 的部分支持，并被选为指导委员会第一任主席。该奖项的研究方面将在 BEACON 的背景下进行，包括：i) 对收集到的数据和组织进行持续分析，这些数据和组织作为 Barrett 事件社区病例对照研究的一部分进行分析，Vaughan 博士是该研究的负责人，ii) 对 BEACON 调查人员进行的多项基于人群的研究的数据进行汇总分析，以及 iii) 在 BEACON 内开发新的合作研究项目，利用所代表的不同人群和现有的数据库 特征良好的组织。沃恩博士在指导研究生和博士后研究员以及流行病学和相关学科的初级教师方面拥有良好的记录。 1990年至2006年，他担任环境流行病学培训补助金的联合主任； 2005 年，他担任 NCI 资助的癌症流行病学和生物统计学培训补助金 (T32CA09168) 的主任。他是流行病学课程的常客讲师，并曾在 23 个硕士论文委员会和 20 个博士论文委员会任职。 K05 的扩展指导活动将包括：i）与他在培训补助金方面的职责相关的活动，ii）他对来自流行病学和相关部门的其他学员以及 UW 和 FHCRC 公共卫生学科的初级教师的持续指导，以及 iii）两名直接从事 K05 相关研究活动的新博士前或博士后学生。