ANALYSIS OF PARTIALLY RECONSTITUTED KINETOCHORE

部分重建着丝粒的分析

• 批准号: 8171395
• 负责人: Michael MacCoss
• 金额: $ 0.67万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-01 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8171395
• 关键词: Bacteria; Chromosomes; Complex; Computer Retrieval of Information on Scientific Projects Database; Funding; Grant; Institution; Kinetochores; Microtubules; Mitosis; Proteins; Research; Research Personnel; Resources; Source; United States National Institutes of Health; reconstitution

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The kinetochore is a highly conserved complex responsible for making the attachment between microtubules and chromosomes during mitosis. Although the major sub-complexes of the kinetochore have been identified, relatively little is known about the structural organization of these sub-complexes. We would like to determine which proteins/sub-complexes are copurifying when expressed in bacteria to aid in structural analysis.

这个子项目是众多研究子项目之一