The Chorus Project: A Sustainable Cloud Solution for Mass Spectrometry Data
The Chorus Project: A Sustainable Cloud Solution for Mass Spectrometry Data
批准号:
9216498
负责人:
Michael MacCoss
金额:
$29.36万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2017
资助国家:
美国
项目状态:
已结题
起止时间:
2017-02-01 至 2021-01-31
关键词:
AlgorithmsBiologicalBiological AssayBiomedical ResearchCellsCloud ComputingCommunicationCommunitiesComputer softwareDataData CollectionData FilesData ScienceData SetData Storage and RetrievalDevelopmentDictionaryDiseaseEducational workshopEnsureFoundationsGenesGoalsImageryIndividualLaboratoriesLaboratory ResearchMaintenanceManufacturer NameMass Spectrum AnalysisMedicalMetadataMethodsOntologyOperating SystemPeptidesPerformancePhenotypeProblem SolvingProcessProductionProteomicsPublishingResearch InfrastructureSamplingScienceStandardizationStress TestsSystemTechnologyTestingTimeTrainingVendorapplication programming interfacebiomedical scientistcomputer infrastructurecostcost effectivedata accessdata acquisitiondata formatdata integrationexperimental studyimprovedinstrumentmass spectrometermeetingsnovelnovel strategiesrepositorysearch enginesmall moleculetoolwebinar
中文摘要
项目总结/摘要
合唱团项目(http://www.example.com)的首要目标是通过以下方式推进生物医学研究:
扩展我们的存储、传播、共享和分析世界质量的能力
光谱数据。到目前为止,质谱社区一直将他们的文件存储在本地"筒仓"中。
在各自的研究实验室。每个实验室目前都建立了自己的计算基础设施,
他们的数据分析。这一过程效率低下,而且重复。实验室共享机制,
以协作方式分析数据几乎不存在。此外,无论是供应商数据格式,
建立的储存库也不能使在实验之间进行分析变得可行或有效,
laboratories.我们已经开发了一个云基础设施,可以促进高效的存储,共享,
跨供应商平台的质谱数据可视化。我们打算在这个基础上,
使社区能够构建工具来访问和分析单个数据集或集体数据,
整体通过将数据引入共享的云基础架构,我们可以改进可能的分析,
最大限度地减少共享大型数据集的挑战,并降低总体成本。我们将提高价值
通过工具标准化、提高数据可访问性、增加共享,
更有效的数据访问和更好的沟通。
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英文摘要
PROJECT SUMMARY/ABSTRACT
The overarching goal of the Chorus project (http://chorusproject.org) is to advance biomedical research by
extending our capabilities for the storage, dissemination, sharing, and analysis of the world's mass
spectrometry data. To date, the mass spectrometry community has been storing their files in local “silos”
within the respective research laboratory. Each lab currently builds their own computational infrastructure for
the analysis of their data. This process is inefficient and redundant. Mechanisms for labs to share and
analyze data in a collaborative manner are almost non-existent. Furthermore, neither the vendor data formats,
nor the established repositories make it feasible or efficiently to perform analyses between experiments and
laboratories. We have developed a cloud infrastructure that facilitates the efficient storage, sharing, and
visualization of mass spectrometry data across vendor platforms. We intend to build on this foundation for
enabling the community to build tools to access and analyze individual datasets or the collective data as a
whole. By bringing data into a shared cloud infrastructure, we improve the analyses that are possible,
minimize the challenges with sharing large datasets, and reduce the overall costs. We will improve the value
of all mass spectrometry data through standardization of tools, improved data accessibility, increased sharing,
more efficient data access, and better communication.
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会议论文
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批准号:10609502
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财政年份:2021
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负责人:Michael MacCoss
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依托单位:
Seattle Quant: A Resource for the Skyline Software Ecosystem
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批准号:10400105
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资助金额:$111.38万
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财政年份:2021
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负责人:Michael MacCoss
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依托单位:
Seattle Quant: A Resource for the Skyline Software Ecosystem
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批准号:10189938
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批准号:10359192
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负责人:Michael MacCoss
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依托单位:
Project 1: Discovery of proteins with altered abundance and stability
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批准号:10573256
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资助金额:$48.48万
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财政年份:2020
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负责人:Michael MacCoss
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Next Generation Translational Proteomics for Alzheimer's and Related Dementias
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批准号:10573244
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资助金额:$314.46万
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财政年份:2020
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负责人:Michael MacCoss
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依托单位:
Core 1: Administrative Core
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批准号:10573245
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项目类别:
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资助金额:$5.64万
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财政年份:2020
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负责人:Michael MacCoss
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依托单位:
Next Generation Translational Proteomics for Alzheimer's and Related Dementias
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批准号:10359187
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项目类别:
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资助金额:$314.46万
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财政年份:2020
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负责人:Michael MacCoss
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依托单位:
Core 1: Administrative Core
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批准号:10359188
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项目类别:
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资助金额:$11.34万
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财政年份:2020
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负责人:Michael MacCoss
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依托单位:
The biofilm matrix of P. aeruginosa
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批准号:10579223
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资助金额:$53.99万
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财政年份:2019
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负责人:Michael MacCoss
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依托单位:
The biofilm matrix of P. aeruginosa
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批准号:10330563
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项目类别:
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资助金额:$56.71万
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财政年份:2019
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负责人:Michael MacCoss
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依托单位:
Systematic and Comprehensive Sampling of Peptides in Mixtures by Tandem Mass Spectrometry
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批准号:8850241
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项目类别:
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资助金额:$19.38万
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财政年份:2015
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负责人:Michael MacCoss
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依托单位:
Systematic and Comprehensive Sampling of Peptides in Mixtures by Tandem Mass Spectrometry
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批准号:9052745
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项目类别:
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资助金额:$22.73万
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财政年份:2015
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负责人:Michael MacCoss
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依托单位:
Self Correcting Nanoflow LC-MS for Clinical Proteomics
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批准号:8840976
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项目类别:
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资助金额:$37.43万
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财政年份:2013
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负责人:Michael MacCoss
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依托单位:
Self Correcting Nanoflow LC-MS for Clinical Proteomics
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批准号:8558710
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项目类别:
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资助金额:$35.59万
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财政年份:2013
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负责人:Michael MacCoss
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依托单位:
Skyline Targeted Proteomics Environment
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批准号:8217996
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项目类别:
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资助金额:$37.98万
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财政年份:2011
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负责人:Michael MacCoss
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依托单位:
Skyline Targeted Proteomics Environment
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批准号:8915218
-
项目类别:
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资助金额:$38.63万
-
财政年份:2011
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负责人:Michael MacCoss
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依托单位:
Skyline Targeted Proteomics Environment
-
批准号:8539058
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项目类别:
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资助金额:$37.27万
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财政年份:2011
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负责人:Michael MacCoss
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依托单位:
DEVELOPMENT OF CUSTOM FAIMS ELECTRONICS
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批准号:8365834
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项目类别:
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资助金额:$0.95万
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财政年份:2011
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负责人:Michael MacCoss
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依托单位:
OPTIMIZATION OF NANOFLOW LC FOR IMPROVED PEAK CAPACITY AND PEPTIDE IDS
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批准号:8365816
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项目类别:
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资助金额:$0.95万
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财政年份:2011
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负责人:Michael MacCoss
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依托单位:
海外基金