CORRELATING MULTIPLE LABELING WITH ARRAY TOMOGRAPHY AND ELECTRON TOMOGRAPHY

将多重标记与阵列断层扫描和电子断层扫描相关联

• 批准号: 8169627
• 负责人: STEPHEN D SMITH
• 金额: $ 0.96万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-04-01 至 2011-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8169627
• 关键词: Area; Cells; Computer Retrieval of Information on Scientific Projects Database; Data; Databases; Development; Electron Microscopy; Environment; Funding; Goals; Grant; Institution; Label; Microchemistry; Neuropil; Preparation; Research; Research Personnel; Resources; Source; Specimen; Synapses; Technology; United States National Institutes of Health; electron tomography; federated computing; light microscopy; reconstruction; research and development; tomography

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The goal of this collaborative project is to leverage and help drive NCMIR research and development activities in areas of specimen preparation for correlated light microscopy (LM) and electron microscopy (EM) that preserve antigenicity and microstructure in ways that contribute to the further development of our new array tomography reconstruction technology. We also plan to integrate our project data about microchemistry of multiple synapses in neuropil with the multi-scale, federated data environment of the NCMIR Cell Centered Database.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 该合作项目的目标是利用和帮助推动NCMIR在相关光学显微镜（LM）和电子显微镜（EM）标本制备领域的研究和开发活动，以有助于我们新的阵列断层扫描重建技术的进一步发展的方式保留抗原性和微观结构。我们还计划将我们关于神经元中多个突触的微化学的项目数据与NCMIR细胞中心数据库的多尺度联合数据环境相结合。