HIGH FIELD MRI: LIMITATIONS AND SOLUTIONS

高场 MRI：局限性和解决方案

• 批准号: 8170477
• 负责人: Christopher M Collins
• 金额: $ 0.64万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-06-01 至 2011-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8170477
• 关键词: Anatomic Models; Computer Retrieval of Information on Scientific Projects Database; Contracts; Development; Funding; Grant; Human; Image; Institution; Magnetic Resonance Imaging; Medical center; Minnesota; Research; Research Personnel; Resources; Solutions; Source; United States National Institutes of Health; Validation; Work; Yang; simulation

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Drs. Chris Collins, Qing Yang, Vaughan, Garwood, Ugurbil, and respective staffs are collaborating to identify and characterize the limitations, and to discover and develop new solution for MRI of humans at 7T and higher. The Penn State Hershey Medical Center Lab of Drs. Collins and Yang (formerly that of Dr. Michael Smith), has pioneered the development of high fidelity, highly segmented human anatomic models for numerical simulations of SNR, SAR, B1 uniformity and other physical parameters. Through theoretical simulation and empirical validation, we are able to explore the problems and find new solutions to human imaging at unprecedented field strengths. This work is supported in part by a Minnesota sub-contract to Penn State's NIH-PAR-02-010, and by Penn State's subcontract with Vaughan's NIH-EB000895.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 Drs. Chris柯林斯、Qing Yang、Vaughan、Garwood、Ugurbil和各自的工作人员正在合作，以确定和描述局限性，并发现和开发7 T及更高温度下人体MRI的新解决方案。柯林斯博士和杨博士（原迈克尔·史密斯博士）的宾夕法尼亚州立大学好时医学中心实验室率先开发了高保真度、高度分段的人体解剖模型，用于SNR、SAR、B1均匀性和其他物理参数的数值模拟。 通过理论模拟和经验验证，我们能够探索问题，并找到新的解决方案，在前所未有的场强人体成像。 这项工作部分得到了明尼苏达州与宾夕法尼亚州立大学的NIH-PAR-02-010的分包合同的支持，并得到了宾夕法尼亚州立大学与沃恩的NIH-EB 000895的合作。