HIGH FIELD MRI: LIMITATIONS AND SOLUTIONS

高场 MRI：局限性和解决方案

• 批准号: 8170477
• 负责人: Christopher M Collins
• 金额: $ 0.64万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-06-01 至 2011-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8170477
• 关键词: Anatomic Models; Computer Retrieval of Information on Scientific Projects Database; Contracts; Development; Funding; Grant; Human; Image; Institution; Magnetic Resonance Imaging; Medical center; Minnesota; Research; Research Personnel; Resources; Solutions; Source; United States National Institutes of Health; Validation; Work; Yang; simulation

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Drs. Chris Collins, Qing Yang, Vaughan, Garwood, Ugurbil, and respective staffs are collaborating to identify and characterize the limitations, and to discover and develop new solution for MRI of humans at 7T and higher. The Penn State Hershey Medical Center Lab of Drs. Collins and Yang (formerly that of Dr. Michael Smith), has pioneered the development of high fidelity, highly segmented human anatomic models for numerical simulations of SNR, SAR, B1 uniformity and other physical parameters. Through theoretical simulation and empirical validation, we are able to explore the problems and find new solutions to human imaging at unprecedented field strengths. This work is supported in part by a Minnesota sub-contract to Penn State's NIH-PAR-02-010, and by Penn State's subcontract with Vaughan's NIH-EB000895.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 博士。克里斯·柯林斯（Chris Collins），清阳，沃恩（Vaughan），加伍德（Garwood），乌不利比尔（Ugurbil）和各自的员工正在合作识别和表征局限性，并在7T及更高范围内发现并为人类的MRI发现和开发新的解决方案。宾夕法尼亚州赫尔希医学中心博士实验室。柯林斯和杨（以前是迈克尔·史密斯（Michael Smith）博士）率先开发了高保真性，高度分割的人类解剖模型，用于SNR，SAR，B1均匀性和其他物理参数的数值模拟。 通过理论模拟和经验验证，我们能够探索问题并在前所未有的现场强度下找到人类成像的新解决方案。 这项工作部分由明尼苏达州的NIH-PAR-02-010的明尼苏达州分包合同，以及宾夕法尼亚州立大学与沃恩的NIH-EB000895的分包合同。