HIGH FIELD MRI: LIMITATIONS AND SOLUTIONS

高场 MRI：局限性和解决方案

• 批准号: 8362872
• 负责人: Christopher M Collins
• 金额: $ 0.76万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-06-01 至 2012-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8362872
• 关键词: Anatomic Models; Contracts; Development; Funding; Grant; Human; Image; Magnetic Resonance Imaging; Medical center; Minnesota; NMR Spectroscopy; National Center for Research Resources; Principal Investigator; Research; Research Infrastructure; Resources; Solutions; Source; United States National Institutes of Health; Validation; Work; Yang; cost; simulation

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Drs. Chris Collins, Qing Yang, Vaughan, Garwood, Ugurbil, and respective staffs are collaborating to identify and characterize the limitations, and to discover and develop new solution for MRI of humans at 7T and higher. The Penn State Hershey Medical Center Lab of Drs. Collins and Yang (formerly that of Dr. Michael Smith), has pioneered the development of high fidelity, highly segmented human anatomic models for numerical simulations of SNR, SAR, B1 uniformity and other physical parameters. Through theoretical simulation and empirical validation, we are able to explore the problems and find new solutions to human imaging at unprecedented field strengths. This work is supported in part by a Minnesota sub-contract to Penn State's NIH-PAR-02-010, and by Penn State's subcontract with Vaughan's NIH-EB000895.

该子项目是利用资源的众多研究子项目之一 由 NIH/NCRR 资助的中心拨款提供。子项目的主要支持 并且子项目的主要研究者可能是由其他来源提供的， 包括其他 NIH 来源。 子项目可能列出的总成本 代表子项目使用的中心基础设施的估计数量， NCRR 赠款不直接向子项目或子项目工作人员提供资金。 博士。 Chris Collins、Qing Yang、Vaughan、Garwood、Ugurbil 和各自的工作人员正在合作识别和描述其局限性，并发现和开发 7T 及更高频率下人类 MRI 的新解决方案。宾夕法尼亚州立大学赫尔希医学中心博士实验室。 Collins 和 Yang（前 Michael Smith 博士）率先开发了高保真、高度分段的人体解剖模型，用于 SNR、SAR、B1 均匀性和其他物理参数的数值模拟。 通过理论模拟和实证验证，我们能够在前所未有的场强下探索问题并找到人体成像的新解决方案。 这项工作部分得到明尼苏达州与宾夕法尼亚州立大学 NIH-PAR-02-010 的分包合同以及宾夕法尼亚州立大学与旺市 NIH-EB000895 的分包合同的支持。