UNDERGRADUATE AND MEDICAL STUDENT RESEARCH PROJECTS

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 在资源总监和工作人员的指导下，学生们参加了2009-10学年波士顿大学本科生研究机会计划和医科学生研究计划下的MS资源研究。波士顿大学化学系。学生们在一年一度的本科生研究研讨会上就他们的工作做报告。来自其他机构的本科生也有资格在资源中心进行研究。 Nikhil Madhuudhan先生是一名化学专业的学生，于2007年秋季加入The Resources。他选择就读波士顿大学，很大程度上是基于有机会在资源/CPC进行研究。他正在进行的项目包括将电泳蛋白质分离作为我们的蛋白质森林设备的Beta测试的一部分，并正在使用这个设备来研究淀粉样蛋白转甲状腺蛋白的氧化翻译后修饰。 Paul Romesser先生在资源合作者Gerald Denis的指导下工作了几年。他一直密切参与Brd2复合体的蛋白质组学研究。他在2005年由Costello教授和Mann教授组织的Keystone会议和2007年ASMS会议上展示了他的研究海报。2006年夏天，罗梅瑟先生获得了特别资金，让他可以在资源和CPC全职工作。罗梅瑟于2006年秋季开始在BUSM学习医学，但一直在The Resources从事研究工作。在本报告所述期间，出版了一份描述他的成果的新手稿。在本学年，他在霍华德·休斯基金会的项目下，在国立卫生研究院进行了第二年的研究。 Zaia教授已经聘请了一群计算机科学专业的本科生参与该项目，开发支持多糖分析的软件。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Guided by the Resource Directors and staff, students participated in MS Resource research under the Boston University Undergraduate Research Opportunities Program and programs for medical student research in the 2009-10 academic year. Boston University Chemistry Dept. students make presentations on their work at the annual Undergraduate Research Symposium. Undergraduates from other institutions are also eligible to conduct research at the Resource. Mr. Nikhil Madhusudhan is a chemistry major and joined the Resource in fall 2007. His choice to attend BU was strongly based on the opportunity to perform researdh at the Resource/CPC. He is working on projects that involve electrophoretic protein separation as part of our beta-test of the Protein Forest device and is using this device in his investigation of oxidative post-translational modifications of the amyloid protein transthyretin. Mr. Paul Romesser has worked under the direction of Resource collaborator Gerald Denis for several years. He has been closely involved in proteomics studies of Brd2 complexes. He presented poster on his research at the 2005 Keystone Conference organized by Prof. Costello and Prof. Mann and at the 2007 ASMS meeting. For the summer of 2006, Mr. Romesser received special funding to allow him to work full time at the Resource and CPC. Mr. Romesser began his medical studies at BUSM in Fall 2006 but has continued to carry out research at the Resource. A new manuscript describing his results was published during this reporting period. During this academic year he is performing a second year of research at NIH, under a Howard Hughes Foundation program. Prof. Zaia has engaged a group of undergraduate students in the Computer Science program in the project to develop software to support glycan analysis.