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NOVEL RECOMBINANT ADENOVIRUS VACCINE VECTORS FOR HIV/SIV IN RHESUS MONKEYS

NOVEL RECOMBINANT ADENOVIRUS VACCINE VECTORS FOR HIV/SIV IN RHESUS MONKEYS
用于恒河猴 HIV/SIV 的新型重组腺病毒疫苗载体
批准号：
8172824
负责人：
Dan H. Barouch
金额：
$6.58万
依托单位：
HARVARD MEDICAL SCHOOL
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
项目状态：
已结题
起止时间：
2010-05-01 至 2011-04-30
来源：
https://reporter.nih.gov/project-details/8172824
关键词：
AddressAdenovirus VectorAdenovirusesAntigensComputer Retrieval of Information on Scientific Projects DatabaseFundingGrantHIV-1HIV-1 vaccineImmuneInstitutionMacaca mulattaRecombinantsResearchResearch PersonnelResourcesSerotypingSourceUnited States National Institutes of HealthVirusnext generationnovelvectorvector vaccinevector-based vaccine

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中文摘要
翻译
这个子项目是众多研究子项目之一
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Next generation HIV-1 vaccines will require more potent vectors as well as antigens that address the challenge of global virus diversity. We have therefore developed novel replication-incompetent adenovirus vector-based vaccines derived from rare adenovirus serotypes as well as mosaic HIV-1 antigens to expand cellular immune breadth and depth.
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NHP Core
Multi-Omics Analysis of Broadly Neutralizing Antibodies and Therapeutic Vaccination
Administrative Core
Multi-Omics Correlates of Broadly Neutralizing Antibody Efficacy
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