RECOMBINANT MEASLES VIRUS AS HIV-1 VACCINE VECTOR IN RHESUS MONKEYS

重组麻疹病毒作为恒河猴 HIV-1 疫苗载体

• 批准号: 8172907
• 负责人: NORMAN L LETVIN
• 金额: $ 6.58万
• 依托单位: HARVARD MEDICAL SCHOOL
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-05-01 至 2011-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8172907
• 关键词: Antigens; Computer Retrieval of Information on Scientific Projects Database; Drug Formulations; Funding; Grant; Institution; Macaca mulatta; Measles virus; Recombinants; Regimen; Research; Research Personnel; Resources; Route; Source; T cell response; Testing; United States National Institutes of Health; Vaccination; Vaccines; base; nonhuman primate; vector vaccine

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. To test Measles virus (MV)-based vaccines, routes of administration, and vaccination formulations in nonhuman primates, specifically to assess the effects on antigen-specific B and T cell responses and to evaluate the vaccination regimens.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 在非人灵长类动物中测试基于麻疹病毒（MV）的疫苗、给药途径和疫苗接种制剂，特别是评估对抗原特异性B和T细胞反应的影响并评估疫苗接种方案。