NEUROBEHAVIORAL BASES OF EMOTION REGULATION AND DYSREGULATION IN ADOLESCENCE

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 全标题：青春期情绪调节和调节失调的神经行为基础：导致焦虑和抑郁风险的发育机制 目的：了解青少年易患应激性精神病的神经回路和分子机制。 使用microPET图像，根据行为挑战期间杏仁核的高、中、低反应性来定义组。在搬迁压力前后，这些受试者在行为和生理上都有了进一步的特征。这些数据将被用来定义导致精神病理学脆弱性的参数。 这项研究使用了WNPRC动物服务部、病理学、运营服务部和图书情报服务部。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Full Title: NEUROBEHAVIORAL BASES OF EMOTION REGULATION AND DYSREGULATION IN ADOLESCENCE: DEVELOPMENTAL MECHANISMS UNDERLYING THE RISK TO DEVELOP ANXIETY AND DEPRESSION Objective: To understand the neural circuits and molecular mechanisms underlying the adolescent vulnerability to develop stress-induced psychopathology. Using microPET images, groups were defined based on high, middle, and low amygdala reactivity during a behavioral challenge. These subjects have been further characterized behaviorally and physiologically both prior to and following relocation stress. These data will be used to define the parameters that engender vulnerability to psychopathology. This research used WNPRC Animal Services, Pathology, Operational Services, and Library and Information services.